Association between a body shape index and bone mineral density in US adults based on NHANES data
Abstract The relationship between a body shape index (ABSI) and bone mineral density (BMD) remains uncertain, prompting further investigation. This study aims to elucidate the association between ABSI and BMD using data from the 2011–2018 National Health and Nutrition Examination Survey (NHANES), in...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-01-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-86939-3 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832585847150477312 |
|---|---|
| author | Jiabei Wu Guiping Wu |
| author_facet | Jiabei Wu Guiping Wu |
| author_sort | Jiabei Wu |
| collection | DOAJ |
| description | Abstract The relationship between a body shape index (ABSI) and bone mineral density (BMD) remains uncertain, prompting further investigation. This study aims to elucidate the association between ABSI and BMD using data from the 2011–2018 National Health and Nutrition Examination Survey (NHANES), involving participants aged 20–60. ABSI was calculated using the formula: ABSI = 1000 × waist circumference (m)×weight (kg)−2/3×height (m)5/6. The analysis employed weighted multiple linear regression, smooth curve fitting, stratified analysis, and interaction tests to explore the relationship between ABSI and total BMD. The study included 10,291 participants, with a mean age of 39.11 ± 10.77 years, and 49.20% were women. The average ABSI was 80.21 ± 1.50. Total BMD, thoracic spine BMD, lumbar spine BMD, and pelvis BMD were measured, with mean values of 0.82 ± 0.11 g/cm², 1.03 ± 0.15 g/cm², and 1.24 ± 0.16 g/cm2, respectively. A negative correlation between ABSI and total BMD was observed. In the fully adjusted model, individuals in the highest ABSI quartile had total BMD levels 0.045 g/cm² lower than those in the lowest quartile. Interaction tests showed a consistent association between ABSI and total BMD across subgroups, with variations in sex and BMI. This analysis of NHANES data confirms a persistent negative association between ABSI and BMD, suggesting that ABSI could be useful in osteoporosis prevention and diagnosis. |
| format | Article |
| id | doaj-art-6d7417eb129c421fb69a317e3fae7fbc |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-6d7417eb129c421fb69a317e3fae7fbc2025-01-26T12:26:36ZengNature PortfolioScientific Reports2045-23222025-01-011511910.1038/s41598-025-86939-3Association between a body shape index and bone mineral density in US adults based on NHANES dataJiabei Wu0Guiping Wu1Shanxi Medical UniversityThe Fifth Hospital of Shanxi Medical University (Shanxi Provincial People’s Hospital)Abstract The relationship between a body shape index (ABSI) and bone mineral density (BMD) remains uncertain, prompting further investigation. This study aims to elucidate the association between ABSI and BMD using data from the 2011–2018 National Health and Nutrition Examination Survey (NHANES), involving participants aged 20–60. ABSI was calculated using the formula: ABSI = 1000 × waist circumference (m)×weight (kg)−2/3×height (m)5/6. The analysis employed weighted multiple linear regression, smooth curve fitting, stratified analysis, and interaction tests to explore the relationship between ABSI and total BMD. The study included 10,291 participants, with a mean age of 39.11 ± 10.77 years, and 49.20% were women. The average ABSI was 80.21 ± 1.50. Total BMD, thoracic spine BMD, lumbar spine BMD, and pelvis BMD were measured, with mean values of 0.82 ± 0.11 g/cm², 1.03 ± 0.15 g/cm², and 1.24 ± 0.16 g/cm2, respectively. A negative correlation between ABSI and total BMD was observed. In the fully adjusted model, individuals in the highest ABSI quartile had total BMD levels 0.045 g/cm² lower than those in the lowest quartile. Interaction tests showed a consistent association between ABSI and total BMD across subgroups, with variations in sex and BMI. This analysis of NHANES data confirms a persistent negative association between ABSI and BMD, suggesting that ABSI could be useful in osteoporosis prevention and diagnosis.https://doi.org/10.1038/s41598-025-86939-3A body shape indexNHANESBone mineral densityOsteoporosisCross-sectional study |
| spellingShingle | Jiabei Wu Guiping Wu Association between a body shape index and bone mineral density in US adults based on NHANES data Scientific Reports A body shape index NHANES Bone mineral density Osteoporosis Cross-sectional study |
| title | Association between a body shape index and bone mineral density in US adults based on NHANES data |
| title_full | Association between a body shape index and bone mineral density in US adults based on NHANES data |
| title_fullStr | Association between a body shape index and bone mineral density in US adults based on NHANES data |
| title_full_unstemmed | Association between a body shape index and bone mineral density in US adults based on NHANES data |
| title_short | Association between a body shape index and bone mineral density in US adults based on NHANES data |
| title_sort | association between a body shape index and bone mineral density in us adults based on nhanes data |
| topic | A body shape index NHANES Bone mineral density Osteoporosis Cross-sectional study |
| url | https://doi.org/10.1038/s41598-025-86939-3 |
| work_keys_str_mv | AT jiabeiwu associationbetweenabodyshapeindexandbonemineraldensityinusadultsbasedonnhanesdata AT guipingwu associationbetweenabodyshapeindexandbonemineraldensityinusadultsbasedonnhanesdata |