Relationship between serum lipids and depression: A cross sectional survey among adults in Haryana, India
Introduction: Dyslipidemia and mental illnesses are significant contributors to the global noncommunicable disease burden and studies suggest an association between them. Aim: Using data from a noncommunicable disease risk factor survey conducted in Haryana, India, we undertook a secondary data anal...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Indian Journal of Psychiatry |
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| Online Access: | https://journals.lww.com/10.4103/indianjpsychiatry.indianjpsychiatry_967_21 |
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| author | Rubina Mulchandani Tanica Lyngdoh Ria Nangia Sukriti Singh Sandeep Grover JS Thakur |
| author_facet | Rubina Mulchandani Tanica Lyngdoh Ria Nangia Sukriti Singh Sandeep Grover JS Thakur |
| author_sort | Rubina Mulchandani |
| collection | DOAJ |
| description | Introduction:
Dyslipidemia and mental illnesses are significant contributors to the global noncommunicable disease burden and studies suggest an association between them.
Aim:
Using data from a noncommunicable disease risk factor survey conducted in Haryana, India, we undertook a secondary data analysis to examine the association between lipids and depressive symptoms.
Methods:
The survey involved 5,078 participants and followed the World Health Organisation STEPwise approach to NCD risk factor surveillance approach. Biochemical assessments were undertaken in a subset of participants. Lipid markers were measured using wet chemistry methods. Depressive symptoms were assessed using the Patient Health Questionnaire–9. Descriptive statistics were presented for all variables; logistic regression was used for association analyses.
Results:
The mean age of the study population was 38 years and 55% of them were females. A majority of the participants belonged to a rural background. The mean total cholesterol was 176 mg/dL and approximately 5% of the participants were found to have moderate to severe depression. The association of total cholesterol (odds ratio [OR] 0.99, P = 0.84), LDL-cholesterol (OR = 1.00, P = 0.19), HDL-cholesterol (OR = 0.99, P = .76), and triglycerides (OR 1.00, P = .12) with depressive symptoms was not significant.
Conclusion:
This study did not find any association between lipids and depressive symptoms. However, further investigations using prospective designs are warranted to understand this relationship and complex interactions with other mediating factors better. |
| format | Article |
| id | doaj-art-6d667c3931b84575af7acb6f5f4ac37a |
| institution | Kabale University |
| issn | 0019-5545 1998-3794 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Psychiatry |
| spelling | doaj-art-6d667c3931b84575af7acb6f5f4ac37a2025-01-20T10:57:50ZengWolters Kluwer Medknow PublicationsIndian Journal of Psychiatry0019-55451998-37942023-01-01651616710.4103/indianjpsychiatry.indianjpsychiatry_967_21Relationship between serum lipids and depression: A cross sectional survey among adults in Haryana, IndiaRubina MulchandaniTanica LyngdohRia NangiaSukriti SinghSandeep GroverJS ThakurIntroduction: Dyslipidemia and mental illnesses are significant contributors to the global noncommunicable disease burden and studies suggest an association between them. Aim: Using data from a noncommunicable disease risk factor survey conducted in Haryana, India, we undertook a secondary data analysis to examine the association between lipids and depressive symptoms. Methods: The survey involved 5,078 participants and followed the World Health Organisation STEPwise approach to NCD risk factor surveillance approach. Biochemical assessments were undertaken in a subset of participants. Lipid markers were measured using wet chemistry methods. Depressive symptoms were assessed using the Patient Health Questionnaire–9. Descriptive statistics were presented for all variables; logistic regression was used for association analyses. Results: The mean age of the study population was 38 years and 55% of them were females. A majority of the participants belonged to a rural background. The mean total cholesterol was 176 mg/dL and approximately 5% of the participants were found to have moderate to severe depression. The association of total cholesterol (odds ratio [OR] 0.99, P = 0.84), LDL-cholesterol (OR = 1.00, P = 0.19), HDL-cholesterol (OR = 0.99, P = .76), and triglycerides (OR 1.00, P = .12) with depressive symptoms was not significant. Conclusion: This study did not find any association between lipids and depressive symptoms. However, further investigations using prospective designs are warranted to understand this relationship and complex interactions with other mediating factors better.https://journals.lww.com/10.4103/indianjpsychiatry.indianjpsychiatry_967_21depressiondyslipidemialipidsmental healthnoncommunicable diseases |
| spellingShingle | Rubina Mulchandani Tanica Lyngdoh Ria Nangia Sukriti Singh Sandeep Grover JS Thakur Relationship between serum lipids and depression: A cross sectional survey among adults in Haryana, India Indian Journal of Psychiatry depression dyslipidemia lipids mental health noncommunicable diseases |
| title | Relationship between serum lipids and depression: A cross sectional survey among adults in Haryana, India |
| title_full | Relationship between serum lipids and depression: A cross sectional survey among adults in Haryana, India |
| title_fullStr | Relationship between serum lipids and depression: A cross sectional survey among adults in Haryana, India |
| title_full_unstemmed | Relationship between serum lipids and depression: A cross sectional survey among adults in Haryana, India |
| title_short | Relationship between serum lipids and depression: A cross sectional survey among adults in Haryana, India |
| title_sort | relationship between serum lipids and depression a cross sectional survey among adults in haryana india |
| topic | depression dyslipidemia lipids mental health noncommunicable diseases |
| url | https://journals.lww.com/10.4103/indianjpsychiatry.indianjpsychiatry_967_21 |
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