B blood type indicates poorer overall survival in patients with severe burn injuries: a case-control study
Introduction This study focuses on the prognostic impact of ABO blood type in patients with severe burn injuries, particularly following the Kunshan explosion, exploring an under-investigated area of burn injury outcomes.Method Data from patients admitted after the Kunshan explosion were analyzed, u...
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Taylor & Francis Group
2025-12-01
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| Series: | Annals of Medicine |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/07853890.2025.2548046 |
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| author | Wei Zhang Xinru Wu Yifan Liu Yuntao Yao Xirui Tong Linhui Li Dayuan Xu Junqiang Li Shuyuan Xian Hanlin Sun Jiale Yan Guosheng Wu Long Xu Bingnan Lu Runzhi Huang Shizhao Ji Zhaofan Xia |
| author_facet | Wei Zhang Xinru Wu Yifan Liu Yuntao Yao Xirui Tong Linhui Li Dayuan Xu Junqiang Li Shuyuan Xian Hanlin Sun Jiale Yan Guosheng Wu Long Xu Bingnan Lu Runzhi Huang Shizhao Ji Zhaofan Xia |
| author_sort | Wei Zhang |
| collection | DOAJ |
| description | Introduction This study focuses on the prognostic impact of ABO blood type in patients with severe burn injuries, particularly following the Kunshan explosion, exploring an under-investigated area of burn injury outcomes.Method Data from patients admitted after the Kunshan explosion were analyzed, using chi-square tests and multivariate Cox regression to investigate the relationship between ABO blood type and overall survival (OS). The study utilized various performance metrics, including the receiver operator characteristic curve (ROC), decision curve analysis (DCA) and Kaplan-Meier survival curve, for model assessment, along with a subgroup analysis for associated factors.Result The research identified ABO blood type as an independent prognostic factor in severe burn injuries. It was found that blood type O is associated with better OS, while blood type B is linked to lower OS (p = 0.001). Clinical variables such as acute kidney injury (AKI), sepsis, and other complications influenced the effect of ABO blood type on OS, according to our subgroup analysis.Conclusion Our findings indicated that blood type B was an independent and significant predictor of OS in patients with severe burn injuries, likely due to differences in immune and coagulation responses. Although the study focused on the relationship between blood type and OS, it also highlighted the importance of other factors, such as patient comorbidities and treatment approaches. |
| format | Article |
| id | doaj-art-6d5b9ece16944e938d2592b95aa5c62c |
| institution | Kabale University |
| issn | 0785-3890 1365-2060 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Annals of Medicine |
| spelling | doaj-art-6d5b9ece16944e938d2592b95aa5c62c2025-08-20T07:46:13ZengTaylor & Francis GroupAnnals of Medicine0785-38901365-20602025-12-0157110.1080/07853890.2025.2548046B blood type indicates poorer overall survival in patients with severe burn injuries: a case-control studyWei Zhang0Xinru Wu1Yifan Liu2Yuntao Yao3Xirui Tong4Linhui Li5Dayuan Xu6Junqiang Li7Shuyuan Xian8Hanlin Sun9Jiale Yan10Guosheng Wu11Long Xu12Bingnan Lu13Runzhi Huang14Shizhao Ji15Zhaofan Xia16Department of Burn Surgery, the First Affiliated Hospital of Naval Medical University, Research Unit of key techniques for treatment of burns and combined burns and trauma injury, Chinese Academy of Medical Sciences, Shanghai, ChinaDepartment of Orthopaedic Surgery, Shanghai Ninth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaDepartment of Urology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaDepartment of Urology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaDepartment of Burn Surgery, the First Affiliated Hospital of Naval Medical University, Research Unit of key techniques for treatment of burns and combined burns and trauma injury, Chinese Academy of Medical Sciences, Shanghai, ChinaDepartment of Burn Surgery, the First Affiliated Hospital of Naval Medical University, Research Unit of key techniques for treatment of burns and combined burns and trauma injury, Chinese Academy of Medical Sciences, Shanghai, ChinaDepartment of Burn Surgery, the First Affiliated Hospital of Naval Medical University, Research Unit of key techniques for treatment of burns and combined burns and trauma injury, Chinese Academy of Medical Sciences, Shanghai, ChinaDepartment of Burn Surgery, the First Affiliated Hospital of Naval Medical University, Research Unit of key techniques for treatment of burns and combined burns and trauma injury, Chinese Academy of Medical Sciences, Shanghai, ChinaDepartment of Burn Surgery, the First Affiliated Hospital of Naval Medical University, Research Unit of key techniques for treatment of burns and combined burns and trauma injury, Chinese Academy of Medical Sciences, Shanghai, ChinaDepartment of Burn Surgery, the First Affiliated Hospital of Naval Medical University, Research Unit of key techniques for treatment of burns and combined burns and trauma injury, Chinese Academy of Medical Sciences, Shanghai, ChinaTongji University School of Medicine, Tongji University, Shanghai, ChinaDepartment of Burn Surgery, the First Affiliated Hospital of Naval Medical University, Research Unit of key techniques for treatment of burns and combined burns and trauma injury, Chinese Academy of Medical Sciences, Shanghai, ChinaDepartment of Burn Surgery, the First Affiliated Hospital of Naval Medical University, Research Unit of key techniques for treatment of burns and combined burns and trauma injury, Chinese Academy of Medical Sciences, Shanghai, ChinaDepartment of Urology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaDepartment of Burn Surgery, the First Affiliated Hospital of Naval Medical University, Research Unit of key techniques for treatment of burns and combined burns and trauma injury, Chinese Academy of Medical Sciences, Shanghai, ChinaDepartment of Burn Surgery, the First Affiliated Hospital of Naval Medical University, Research Unit of key techniques for treatment of burns and combined burns and trauma injury, Chinese Academy of Medical Sciences, Shanghai, ChinaDepartment of Burn Surgery, the First Affiliated Hospital of Naval Medical University, Research Unit of key techniques for treatment of burns and combined burns and trauma injury, Chinese Academy of Medical Sciences, Shanghai, ChinaIntroduction This study focuses on the prognostic impact of ABO blood type in patients with severe burn injuries, particularly following the Kunshan explosion, exploring an under-investigated area of burn injury outcomes.Method Data from patients admitted after the Kunshan explosion were analyzed, using chi-square tests and multivariate Cox regression to investigate the relationship between ABO blood type and overall survival (OS). The study utilized various performance metrics, including the receiver operator characteristic curve (ROC), decision curve analysis (DCA) and Kaplan-Meier survival curve, for model assessment, along with a subgroup analysis for associated factors.Result The research identified ABO blood type as an independent prognostic factor in severe burn injuries. It was found that blood type O is associated with better OS, while blood type B is linked to lower OS (p = 0.001). Clinical variables such as acute kidney injury (AKI), sepsis, and other complications influenced the effect of ABO blood type on OS, according to our subgroup analysis.Conclusion Our findings indicated that blood type B was an independent and significant predictor of OS in patients with severe burn injuries, likely due to differences in immune and coagulation responses. Although the study focused on the relationship between blood type and OS, it also highlighted the importance of other factors, such as patient comorbidities and treatment approaches.https://www.tandfonline.com/doi/10.1080/07853890.2025.2548046Burn injuriesABO blood typeKunshan explosion incidentprognostic factorcomorbidities |
| spellingShingle | Wei Zhang Xinru Wu Yifan Liu Yuntao Yao Xirui Tong Linhui Li Dayuan Xu Junqiang Li Shuyuan Xian Hanlin Sun Jiale Yan Guosheng Wu Long Xu Bingnan Lu Runzhi Huang Shizhao Ji Zhaofan Xia B blood type indicates poorer overall survival in patients with severe burn injuries: a case-control study Annals of Medicine Burn injuries ABO blood type Kunshan explosion incident prognostic factor comorbidities |
| title | B blood type indicates poorer overall survival in patients with severe burn injuries: a case-control study |
| title_full | B blood type indicates poorer overall survival in patients with severe burn injuries: a case-control study |
| title_fullStr | B blood type indicates poorer overall survival in patients with severe burn injuries: a case-control study |
| title_full_unstemmed | B blood type indicates poorer overall survival in patients with severe burn injuries: a case-control study |
| title_short | B blood type indicates poorer overall survival in patients with severe burn injuries: a case-control study |
| title_sort | b blood type indicates poorer overall survival in patients with severe burn injuries a case control study |
| topic | Burn injuries ABO blood type Kunshan explosion incident prognostic factor comorbidities |
| url | https://www.tandfonline.com/doi/10.1080/07853890.2025.2548046 |
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