Immune Dysregulation and Trophoblastic Dysfunction as a Potential Cause of Idiopathic Recurrent Pregnancy Loss

Immune Dysregulation and Trophoblastic Dysfunction as a Potential Cause of Idiopathic Recurrent Pregnancy Loss

Recurrent pregnancy loss (RPL) is a multifactorial condition affecting 1–5% of couples, often with unclear etiology. Idiopathic pregnancy losses (iPLs) are particularly challenging due to unknown molecular mechanisms. This study investigates the transcriptomic profiles of first-trimester products of...

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Main Authors: Sara Vasconcelos, Ana Costa Braga, Ioannis Moustakas, Bruno Cavadas, Mariana Santos, Carla Caniçais, Carla Ramalho, Susana M. Chuva de Sousa Lopes, Cristina Joana Marques, Sofia Dória
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Biology
Subjects:
pregnancy loss
transcriptome
cytotrophoblast
syncytiotrophoblast
extravillous trophoblast
immune dysregulation
Online Access:https://www.mdpi.com/2079-7737/14/7/811
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https://www.mdpi.com/2079-7737/14/7/811

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