Oral Squamous Cell Carcinoma in a Patient with Fanconi Anemia
Fanconi anemia (FA) is a rare autosomal recessive genetic disorder characterized by different types of malformations, skin lesions, bone marrow failure, and increased risk for both hematological malignancies and solid tumors, especially head and neck squamous cell carcinomas (HNSCC). FA patients may...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Dentistry |
| Online Access: | http://dx.doi.org/10.1155/2021/5571649 |
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| _version_ | 1832560671790727168 |
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| author | Milla Huuhka Aaro Turunen |
| author_facet | Milla Huuhka Aaro Turunen |
| author_sort | Milla Huuhka |
| collection | DOAJ |
| description | Fanconi anemia (FA) is a rare autosomal recessive genetic disorder characterized by different types of malformations, skin lesions, bone marrow failure, and increased risk for both hematological malignancies and solid tumors, especially head and neck squamous cell carcinomas (HNSCC). FA patients may also display a low tolerance to oncologic treatments. The authors present a case of mandibular squamous cell carcinoma in a young FA patient. Because of the aggressive nature of the SCC and complex treatment options, we recommend a strict lifelong follow-up for all FA patients to detect early changes in the oral mucosa. |
| format | Article |
| id | doaj-art-6d51e0a6472e4de3a324e1cf734a5682 |
| institution | Kabale University |
| issn | 2090-6447 2090-6455 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Dentistry |
| spelling | doaj-art-6d51e0a6472e4de3a324e1cf734a56822025-02-03T01:26:59ZengWileyCase Reports in Dentistry2090-64472090-64552021-01-01202110.1155/2021/55716495571649Oral Squamous Cell Carcinoma in a Patient with Fanconi AnemiaMilla Huuhka0Aaro Turunen1Department of Oral and Maxillofacial Diseases, Turku University Hospital, Turku, FinlandDepartment of Oral and Maxillofacial Diseases, Turku University Hospital, Turku, FinlandFanconi anemia (FA) is a rare autosomal recessive genetic disorder characterized by different types of malformations, skin lesions, bone marrow failure, and increased risk for both hematological malignancies and solid tumors, especially head and neck squamous cell carcinomas (HNSCC). FA patients may also display a low tolerance to oncologic treatments. The authors present a case of mandibular squamous cell carcinoma in a young FA patient. Because of the aggressive nature of the SCC and complex treatment options, we recommend a strict lifelong follow-up for all FA patients to detect early changes in the oral mucosa.http://dx.doi.org/10.1155/2021/5571649 |
| spellingShingle | Milla Huuhka Aaro Turunen Oral Squamous Cell Carcinoma in a Patient with Fanconi Anemia Case Reports in Dentistry |
| title | Oral Squamous Cell Carcinoma in a Patient with Fanconi Anemia |
| title_full | Oral Squamous Cell Carcinoma in a Patient with Fanconi Anemia |
| title_fullStr | Oral Squamous Cell Carcinoma in a Patient with Fanconi Anemia |
| title_full_unstemmed | Oral Squamous Cell Carcinoma in a Patient with Fanconi Anemia |
| title_short | Oral Squamous Cell Carcinoma in a Patient with Fanconi Anemia |
| title_sort | oral squamous cell carcinoma in a patient with fanconi anemia |
| url | http://dx.doi.org/10.1155/2021/5571649 |
| work_keys_str_mv | AT millahuuhka oralsquamouscellcarcinomainapatientwithfanconianemia AT aaroturunen oralsquamouscellcarcinomainapatientwithfanconianemia |