2 Cases of Bullosis Diabeticorum following Long-Distance Journeys by Road: A Report of 2 Cases
Background. Bullosis diabeticorum is a distinct, spontaneous, noninflammatory, and blistering condition of acral skin that is unique to diabetics. It is rare. Exact aetiopathogenesis is not known, but many attributed peripheral neuropathy as a potent risk factor, others hypothesized the role of trau...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2012/367218 |
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| author | Fatima Bello O. Modupe Samaila Yakubu Lawal U. Kufre Nkoro |
| author_facet | Fatima Bello O. Modupe Samaila Yakubu Lawal U. Kufre Nkoro |
| author_sort | Fatima Bello |
| collection | DOAJ |
| description | Background. Bullosis diabeticorum is a distinct, spontaneous, noninflammatory, and blistering condition of acral skin that is unique to diabetics. It is rare. Exact aetiopathogenesis is not known, but many attributed peripheral neuropathy as a potent risk factor, others hypothesized the role of trauma, UV light, and nephropathy. Aim. To present cases of bullosis diabeticorum following long-distance journeys by road. Methods. History and physical examinations were done on 2 diabetics who presented with bilateral feet bullae following a long journey. Biopsy of a circumferential area of the bullae including adjoining apparently normal skin was done. Results. Features of peripheral neuropathy were noted. One developed digital gangrene without features of peripheral vascular disease. Culture of aspirate from a bullae yielded Staphylococcus aureus. Tissue biopsy showed hyperkeratotic focally acanthotic pigmented epidermis with subcorneal separation of the granular layer of the epidermis by aggregates of viable and nonviable polymorphs and lymphocytes. There is mild acantholysis of the epidermis, and a fibrocollagenous dermis which is moderately infiltrated by lymphocytes. Conclusion. Long journeys by road is a strong factor in the aetiopathogenesis of bullosis diabeticorum on a background of peripheral neuropathy. Diabetics especially those with peripheral neuropathy should be cautious while traveling long journeys by road. |
| format | Article |
| id | doaj-art-6d4f8cb6c6be4120b985479c46788104 |
| institution | Kabale University |
| issn | 2090-6501 2090-651X |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-6d4f8cb6c6be4120b985479c467881042025-02-03T06:12:08ZengWileyCase Reports in Endocrinology2090-65012090-651X2012-01-01201210.1155/2012/3672183672182 Cases of Bullosis Diabeticorum following Long-Distance Journeys by Road: A Report of 2 CasesFatima Bello0O. Modupe Samaila1Yakubu Lawal2U. Kufre Nkoro3Endocrine Unit, Department of Medicine, Ahmadu Bello University Teaching Hospital, 810001 Zaria, NigeriaDepartment of Pathology, Ahmadu Bello University Teaching Hospital, 810001 Zaria, NigeriaEndocrine Unit, Department of Medicine, Ahmadu Bello University Teaching Hospital, 810001 Zaria, NigeriaEndocrine Unit, Department of Medicine, Ahmadu Bello University Teaching Hospital, 810001 Zaria, NigeriaBackground. Bullosis diabeticorum is a distinct, spontaneous, noninflammatory, and blistering condition of acral skin that is unique to diabetics. It is rare. Exact aetiopathogenesis is not known, but many attributed peripheral neuropathy as a potent risk factor, others hypothesized the role of trauma, UV light, and nephropathy. Aim. To present cases of bullosis diabeticorum following long-distance journeys by road. Methods. History and physical examinations were done on 2 diabetics who presented with bilateral feet bullae following a long journey. Biopsy of a circumferential area of the bullae including adjoining apparently normal skin was done. Results. Features of peripheral neuropathy were noted. One developed digital gangrene without features of peripheral vascular disease. Culture of aspirate from a bullae yielded Staphylococcus aureus. Tissue biopsy showed hyperkeratotic focally acanthotic pigmented epidermis with subcorneal separation of the granular layer of the epidermis by aggregates of viable and nonviable polymorphs and lymphocytes. There is mild acantholysis of the epidermis, and a fibrocollagenous dermis which is moderately infiltrated by lymphocytes. Conclusion. Long journeys by road is a strong factor in the aetiopathogenesis of bullosis diabeticorum on a background of peripheral neuropathy. Diabetics especially those with peripheral neuropathy should be cautious while traveling long journeys by road.http://dx.doi.org/10.1155/2012/367218 |
| spellingShingle | Fatima Bello O. Modupe Samaila Yakubu Lawal U. Kufre Nkoro 2 Cases of Bullosis Diabeticorum following Long-Distance Journeys by Road: A Report of 2 Cases Case Reports in Endocrinology |
| title | 2 Cases of Bullosis Diabeticorum following Long-Distance Journeys by Road: A Report of 2 Cases |
| title_full | 2 Cases of Bullosis Diabeticorum following Long-Distance Journeys by Road: A Report of 2 Cases |
| title_fullStr | 2 Cases of Bullosis Diabeticorum following Long-Distance Journeys by Road: A Report of 2 Cases |
| title_full_unstemmed | 2 Cases of Bullosis Diabeticorum following Long-Distance Journeys by Road: A Report of 2 Cases |
| title_short | 2 Cases of Bullosis Diabeticorum following Long-Distance Journeys by Road: A Report of 2 Cases |
| title_sort | 2 cases of bullosis diabeticorum following long distance journeys by road a report of 2 cases |
| url | http://dx.doi.org/10.1155/2012/367218 |
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