Evaluation of Anterior Chamber Volume in Cataract Patients with Swept-Source Optical Coherence Tomography

Purpose. To evaluate the anterior chamber volume in cataract patients with Swept-Source Optical Coherence Tomography (SS-OCT) and its influencing factors. Methods. Anterior chamber volume of 92 cataract patients was evaluated with SS-OCT in this cross-sectional study. Univariate analyses and multipl...

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Main Authors: Wenwen He, Xiangjia Zhu, Don Wolff, Zhennan Zhao, Xinghuai Sun, Yi Lu
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2016/8656301
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author Wenwen He
Xiangjia Zhu
Don Wolff
Zhennan Zhao
Xinghuai Sun
Yi Lu
author_facet Wenwen He
Xiangjia Zhu
Don Wolff
Zhennan Zhao
Xinghuai Sun
Yi Lu
author_sort Wenwen He
collection DOAJ
description Purpose. To evaluate the anterior chamber volume in cataract patients with Swept-Source Optical Coherence Tomography (SS-OCT) and its influencing factors. Methods. Anterior chamber volume of 92 cataract patients was evaluated with SS-OCT in this cross-sectional study. Univariate analyses and multiple linear regression were used to investigate gender, age, operated eye, posterior vitreous detachment, lens opacity grading, and axial length (AXL) related variables capable of influencing the ACV. Results. The average ACV was 139.80 ± 38.21 mm3 (range 59.41 to 254.09 mm3). The average ACV was significantly larger in male patients than in female patients (P=0.001). ACV was negatively correlated with age and LOCS III cortical (C) grading of the lens (Pearson’s correlation analysis, r=-0.443, P<0.001, and Spearman’s correlation analysis, ρ=-0.450, P<0.001). ACV was also increased with AXL (Pearson’s correlation analysis, r=0.552, P<0.001). Multiple linear regression showed that, with all of the covariates entered into the model, gender (P=0.002), age (P=0.015), LOCS III C grade (P=0.043), and AXL (P=0.001) were still associated with ACV (F=10.252  P<0.001  R2=0.498). Conclusion. With SS-OCT, we found that, in healthy cataract patients, ACV varied significantly among different subjects. Influencing factors that contribute to reduced ACV were female gender, increased age, LOCS III C grade, and shorter AXL.
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spelling doaj-art-6d3d741d8f6244c2aa7cc0a3f16a5d912025-08-20T02:24:03ZengWileyJournal of Ophthalmology2090-004X2090-00582016-01-01201610.1155/2016/86563018656301Evaluation of Anterior Chamber Volume in Cataract Patients with Swept-Source Optical Coherence TomographyWenwen He0Xiangjia Zhu1Don Wolff2Zhennan Zhao3Xinghuai Sun4Yi Lu5Department of Ophthalmology, Eye and Ear, Nose, and Throat Hospital, Fudan University, 83 Fenyang Road, Shanghai 200031, ChinaDepartment of Ophthalmology, Eye and Ear, Nose, and Throat Hospital, Fudan University, 83 Fenyang Road, Shanghai 200031, ChinaParkway Health Hongqiao Medical Center, 2258 Hongqiao Road, Shanghai 200335, ChinaDepartment of Ophthalmology, Eye and Ear, Nose, and Throat Hospital, Fudan University, 83 Fenyang Road, Shanghai 200031, ChinaDepartment of Ophthalmology, Eye and Ear, Nose, and Throat Hospital, Fudan University, 83 Fenyang Road, Shanghai 200031, ChinaDepartment of Ophthalmology, Eye and Ear, Nose, and Throat Hospital, Fudan University, 83 Fenyang Road, Shanghai 200031, ChinaPurpose. To evaluate the anterior chamber volume in cataract patients with Swept-Source Optical Coherence Tomography (SS-OCT) and its influencing factors. Methods. Anterior chamber volume of 92 cataract patients was evaluated with SS-OCT in this cross-sectional study. Univariate analyses and multiple linear regression were used to investigate gender, age, operated eye, posterior vitreous detachment, lens opacity grading, and axial length (AXL) related variables capable of influencing the ACV. Results. The average ACV was 139.80 ± 38.21 mm3 (range 59.41 to 254.09 mm3). The average ACV was significantly larger in male patients than in female patients (P=0.001). ACV was negatively correlated with age and LOCS III cortical (C) grading of the lens (Pearson’s correlation analysis, r=-0.443, P<0.001, and Spearman’s correlation analysis, ρ=-0.450, P<0.001). ACV was also increased with AXL (Pearson’s correlation analysis, r=0.552, P<0.001). Multiple linear regression showed that, with all of the covariates entered into the model, gender (P=0.002), age (P=0.015), LOCS III C grade (P=0.043), and AXL (P=0.001) were still associated with ACV (F=10.252  P<0.001  R2=0.498). Conclusion. With SS-OCT, we found that, in healthy cataract patients, ACV varied significantly among different subjects. Influencing factors that contribute to reduced ACV were female gender, increased age, LOCS III C grade, and shorter AXL.http://dx.doi.org/10.1155/2016/8656301
spellingShingle Wenwen He
Xiangjia Zhu
Don Wolff
Zhennan Zhao
Xinghuai Sun
Yi Lu
Evaluation of Anterior Chamber Volume in Cataract Patients with Swept-Source Optical Coherence Tomography
Journal of Ophthalmology
title Evaluation of Anterior Chamber Volume in Cataract Patients with Swept-Source Optical Coherence Tomography
title_full Evaluation of Anterior Chamber Volume in Cataract Patients with Swept-Source Optical Coherence Tomography
title_fullStr Evaluation of Anterior Chamber Volume in Cataract Patients with Swept-Source Optical Coherence Tomography
title_full_unstemmed Evaluation of Anterior Chamber Volume in Cataract Patients with Swept-Source Optical Coherence Tomography
title_short Evaluation of Anterior Chamber Volume in Cataract Patients with Swept-Source Optical Coherence Tomography
title_sort evaluation of anterior chamber volume in cataract patients with swept source optical coherence tomography
url http://dx.doi.org/10.1155/2016/8656301
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