A cost-based comparison of quarantine strategies for new emerging diseases

A classical epidemiological framework is used to provide a preliminary cost analysis of the effects of quarantine and isolation on the dynamics of infectious diseases for which no treatment or immediate diagnosis tools are available.Within this framework we consider the cost incurred from the implem...

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Main Authors: Anuj Mubayi, Christopher Kribs Zaleta, Maia Martcheva, Carlos Castillo-Chávez
Format: Article
Language:English
Published: AIMS Press 2010-05-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2010.7.687
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author Anuj Mubayi
Christopher Kribs Zaleta
Maia Martcheva
Carlos Castillo-Chávez
author_facet Anuj Mubayi
Christopher Kribs Zaleta
Maia Martcheva
Carlos Castillo-Chávez
author_sort Anuj Mubayi
collection DOAJ
description A classical epidemiological framework is used to provide a preliminary cost analysis of the effects of quarantine and isolation on the dynamics of infectious diseases for which no treatment or immediate diagnosis tools are available.Within this framework we consider the cost incurred from the implementation of three types of dynamic control strategies. Taking the context of the 2003 SARS outbreak in Hong Kong as an example, we use a simple cost function to compare the total cost of each mixed (quarantine and isolation) control strategy from a public health resource allocation perspective.The goal is to extend existing epi-economics methodology by developing a theoretical framework of dynamic quarantine strategies aimed at emerging diseases, by drawing upon the large body of literature on the dynamics of infectious diseases.We find that the total cost decreases with increases in the quarantine rates past a critical value, regardless of the resource allocation strategy.In the case of a manageable outbreak resources must be used early to achieve the best results whereas in case of an unmanageable outbreak, a constant-effort strategy seems the best among our limited plausible sets.
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institution Kabale University
issn 1551-0018
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publishDate 2010-05-01
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spelling doaj-art-6d305a19fe73407490ed01ece323af902025-01-24T02:00:43ZengAIMS PressMathematical Biosciences and Engineering1551-00182010-05-017368771710.3934/mbe.2010.7.687A cost-based comparison of quarantine strategies for new emerging diseasesAnuj Mubayi0Christopher Kribs Zaleta1Maia Martcheva2Carlos Castillo-Chávez3Mathematical, Computational & Modeling Science Center, Arizona State University, Tempe, AZ 85287-1904Mathematical, Computational & Modeling Science Center, Arizona State University, Tempe, AZ 85287-1904Mathematical, Computational & Modeling Science Center, Arizona State University, Tempe, AZ 85287-1904Mathematical, Computational & Modeling Science Center, Arizona State University, Tempe, AZ 85287-1904A classical epidemiological framework is used to provide a preliminary cost analysis of the effects of quarantine and isolation on the dynamics of infectious diseases for which no treatment or immediate diagnosis tools are available.Within this framework we consider the cost incurred from the implementation of three types of dynamic control strategies. Taking the context of the 2003 SARS outbreak in Hong Kong as an example, we use a simple cost function to compare the total cost of each mixed (quarantine and isolation) control strategy from a public health resource allocation perspective.The goal is to extend existing epi-economics methodology by developing a theoretical framework of dynamic quarantine strategies aimed at emerging diseases, by drawing upon the large body of literature on the dynamics of infectious diseases.We find that the total cost decreases with increases in the quarantine rates past a critical value, regardless of the resource allocation strategy.In the case of a manageable outbreak resources must be used early to achieve the best results whereas in case of an unmanageable outbreak, a constant-effort strategy seems the best among our limited plausible sets.https://www.aimspress.com/article/doi/10.3934/mbe.2010.7.687reproductive numbersarsisolationcost-effectiveness analysis.quarantinecontact tracing
spellingShingle Anuj Mubayi
Christopher Kribs Zaleta
Maia Martcheva
Carlos Castillo-Chávez
A cost-based comparison of quarantine strategies for new emerging diseases
Mathematical Biosciences and Engineering
reproductive number
sars
isolation
cost-effectiveness analysis.
quarantine
contact tracing
title A cost-based comparison of quarantine strategies for new emerging diseases
title_full A cost-based comparison of quarantine strategies for new emerging diseases
title_fullStr A cost-based comparison of quarantine strategies for new emerging diseases
title_full_unstemmed A cost-based comparison of quarantine strategies for new emerging diseases
title_short A cost-based comparison of quarantine strategies for new emerging diseases
title_sort cost based comparison of quarantine strategies for new emerging diseases
topic reproductive number
sars
isolation
cost-effectiveness analysis.
quarantine
contact tracing
url https://www.aimspress.com/article/doi/10.3934/mbe.2010.7.687
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