No Severe Adverse Effects from Intravitreally Injected Putative Adipose Tissue-Derived Stem Cells

This study reports findings from a 56-year-old patient, who had received bilateral intravitreal injection of putative adipose tissue-derived stem cells at a private clinic in India with the promise of treatment of NAION. During an observation period of 8, respectively, 18 months, the intravitreally...

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Main Authors: Carsten Faber, Steffen Heegaard, Jens Folke Kiilgaard
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Ophthalmological Medicine
Online Access:http://dx.doi.org/10.1155/2019/6927829
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author Carsten Faber
Steffen Heegaard
Jens Folke Kiilgaard
author_facet Carsten Faber
Steffen Heegaard
Jens Folke Kiilgaard
author_sort Carsten Faber
collection DOAJ
description This study reports findings from a 56-year-old patient, who had received bilateral intravitreal injection of putative adipose tissue-derived stem cells at a private clinic in India with the promise of treatment of NAION. During an observation period of 8, respectively, 18 months, the intravitreally injected cells remained silent in the vitreous bodies without either therapeutic effects or complications. The cells cleared with vitrectomy without evidence of integration in the optic nerve or retina. Contrary to recent reports on patients receiving intravitreal injections of similar putative stem cells with the aim of treating AMD, our patient suffered no devastating ocular consequences. Summary. Contrary to recent reports, this case demonstrated no devastating consequences of intravitreal injection of adipose tissue-derived stem cells during an observation period of up to 18 months. After vitrectomy, the cells cleared without evidence of either harm or integration.
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institution Kabale University
issn 2090-6722
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publishDate 2019-01-01
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series Case Reports in Ophthalmological Medicine
spelling doaj-art-6d0e77743f62455eb9e212b39be977422025-02-03T01:11:48ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302019-01-01201910.1155/2019/69278296927829No Severe Adverse Effects from Intravitreally Injected Putative Adipose Tissue-Derived Stem CellsCarsten Faber0Steffen Heegaard1Jens Folke Kiilgaard2Department of Ophthalmology, University Hospital Copenhagen, Rigshospitalet, DenmarkDepartment of Ophthalmology, University Hospital Copenhagen, Rigshospitalet, DenmarkDepartment of Ophthalmology, University Hospital Copenhagen, Rigshospitalet, DenmarkThis study reports findings from a 56-year-old patient, who had received bilateral intravitreal injection of putative adipose tissue-derived stem cells at a private clinic in India with the promise of treatment of NAION. During an observation period of 8, respectively, 18 months, the intravitreally injected cells remained silent in the vitreous bodies without either therapeutic effects or complications. The cells cleared with vitrectomy without evidence of integration in the optic nerve or retina. Contrary to recent reports on patients receiving intravitreal injections of similar putative stem cells with the aim of treating AMD, our patient suffered no devastating ocular consequences. Summary. Contrary to recent reports, this case demonstrated no devastating consequences of intravitreal injection of adipose tissue-derived stem cells during an observation period of up to 18 months. After vitrectomy, the cells cleared without evidence of either harm or integration.http://dx.doi.org/10.1155/2019/6927829
spellingShingle Carsten Faber
Steffen Heegaard
Jens Folke Kiilgaard
No Severe Adverse Effects from Intravitreally Injected Putative Adipose Tissue-Derived Stem Cells
Case Reports in Ophthalmological Medicine
title No Severe Adverse Effects from Intravitreally Injected Putative Adipose Tissue-Derived Stem Cells
title_full No Severe Adverse Effects from Intravitreally Injected Putative Adipose Tissue-Derived Stem Cells
title_fullStr No Severe Adverse Effects from Intravitreally Injected Putative Adipose Tissue-Derived Stem Cells
title_full_unstemmed No Severe Adverse Effects from Intravitreally Injected Putative Adipose Tissue-Derived Stem Cells
title_short No Severe Adverse Effects from Intravitreally Injected Putative Adipose Tissue-Derived Stem Cells
title_sort no severe adverse effects from intravitreally injected putative adipose tissue derived stem cells
url http://dx.doi.org/10.1155/2019/6927829
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