The effects of the extract of oolong tea and its metabolites from Andraca theae in high fat diet induced obese Wistar rat
Obesity is a critical health issue worldwide. For a long time, the concept of drinking tea for health and pleasure is widely accepted. The strain of Andraca theae lives on the tea leaf and the bioactivity of its metabolites in the feces is unknown yet. Thus, the objective of this study was to invest...
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| Format: | Article |
| Language: | English |
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Tsinghua University Press
2018-06-01
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| Series: | Food Science and Human Wellness |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213453018300442 |
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| author | Tung Yen-Chen Hsieh Tsung-Hai Yang Meei-Ju Hung Wei-Lun Ho Chi-Tang Pan Min-Hsiung |
| author_facet | Tung Yen-Chen Hsieh Tsung-Hai Yang Meei-Ju Hung Wei-Lun Ho Chi-Tang Pan Min-Hsiung |
| author_sort | Tung Yen-Chen |
| collection | DOAJ |
| description | Obesity is a critical health issue worldwide. For a long time, the concept of drinking tea for health and pleasure is widely accepted. The strain of Andraca theae lives on the tea leaf and the bioactivity of its metabolites in the feces is unknown yet. Thus, the objective of this study was to investigate whether the extract of tea (Taiwan Tea Experiment Station No.12 (TE)) and its metabolites from Andraca theae (TME) could prevent obesity in the high fat diet-induced obese rats. Our results showed that TE had higher concentrations of epigallocatechin gallate (EGCG) and caffeine than that from TME. TE significantly decreased abdominal adipose tissue, especially epididymal fat via increasing preadipocyte factor 1 (Pref-1), SRY (sex determining region Y)-box 9 (SOX-9) and decreasing peroxisome proliferator-activated receptor γ (PPARγ), CCAAT/enhancer binding protein (C/EBP)β, C/EBPα and C/EBPγ protein expression. Taken together, these results suggest that the content of tea polyphenols in TE play an important role for alleviating abdominal fat. Keywords: Tea, Andraca theae, High fat diet, Obesity |
| format | Article |
| id | doaj-art-6d0e547d9fc34296b1865562ed6bc1b3 |
| institution | Kabale University |
| issn | 2213-4530 |
| language | English |
| publishDate | 2018-06-01 |
| publisher | Tsinghua University Press |
| record_format | Article |
| series | Food Science and Human Wellness |
| spelling | doaj-art-6d0e547d9fc34296b1865562ed6bc1b32025-02-03T06:47:45ZengTsinghua University PressFood Science and Human Wellness2213-45302018-06-0172120124The effects of the extract of oolong tea and its metabolites from Andraca theae in high fat diet induced obese Wistar ratTung Yen-Chen0Hsieh Tsung-Hai1Yang Meei-Ju2Hung Wei-Lun3Ho Chi-Tang4Pan Min-Hsiung5Institute of Food Science and Technology, National Taiwan University, Taipei 106, TaiwanInstitute of Food Science and Technology, National Taiwan University, Taipei 106, TaiwanTea Research and Extension Station, Taoyuan 326, TaiwanCitrus Research and Education Center, Department of Food Science and Human Nutrition, University of Florida, Lake Alfred, FL, 33850, USADepartment of Food Science, Rutgers University, New Brunswick, NJ 08901, USAInstitute of Food Science and Technology, National Taiwan University, Taipei 106, Taiwan; Corresponding author at: Institute of Food Science and Technology, National Taiwan University, No. 1, Section 4, Roosevelt Road, Taipei 10617, Taiwan.Obesity is a critical health issue worldwide. For a long time, the concept of drinking tea for health and pleasure is widely accepted. The strain of Andraca theae lives on the tea leaf and the bioactivity of its metabolites in the feces is unknown yet. Thus, the objective of this study was to investigate whether the extract of tea (Taiwan Tea Experiment Station No.12 (TE)) and its metabolites from Andraca theae (TME) could prevent obesity in the high fat diet-induced obese rats. Our results showed that TE had higher concentrations of epigallocatechin gallate (EGCG) and caffeine than that from TME. TE significantly decreased abdominal adipose tissue, especially epididymal fat via increasing preadipocyte factor 1 (Pref-1), SRY (sex determining region Y)-box 9 (SOX-9) and decreasing peroxisome proliferator-activated receptor γ (PPARγ), CCAAT/enhancer binding protein (C/EBP)β, C/EBPα and C/EBPγ protein expression. Taken together, these results suggest that the content of tea polyphenols in TE play an important role for alleviating abdominal fat. Keywords: Tea, Andraca theae, High fat diet, Obesityhttp://www.sciencedirect.com/science/article/pii/S2213453018300442 |
| spellingShingle | Tung Yen-Chen Hsieh Tsung-Hai Yang Meei-Ju Hung Wei-Lun Ho Chi-Tang Pan Min-Hsiung The effects of the extract of oolong tea and its metabolites from Andraca theae in high fat diet induced obese Wistar rat Food Science and Human Wellness |
| title | The effects of the extract of oolong tea and its metabolites from Andraca theae in high fat diet induced obese Wistar rat |
| title_full | The effects of the extract of oolong tea and its metabolites from Andraca theae in high fat diet induced obese Wistar rat |
| title_fullStr | The effects of the extract of oolong tea and its metabolites from Andraca theae in high fat diet induced obese Wistar rat |
| title_full_unstemmed | The effects of the extract of oolong tea and its metabolites from Andraca theae in high fat diet induced obese Wistar rat |
| title_short | The effects of the extract of oolong tea and its metabolites from Andraca theae in high fat diet induced obese Wistar rat |
| title_sort | effects of the extract of oolong tea and its metabolites from andraca theae in high fat diet induced obese wistar rat |
| url | http://www.sciencedirect.com/science/article/pii/S2213453018300442 |
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