YebC2 resolves ribosome stalling and increases fitness of cells lacking EF-P and the ABCF ATPase YfmR.
Ribosome stalling is a major source of cellular stress. Therefore, many specialized elongation factors help prevent ribosome stalling. One of the best characterized of these factors is EF-P, which prevents ribosome stalling at polyproline tracts and other difficult-to-translate sequences. Recent evi...
Saved in:
| Main Authors: | Hye-Rim Hong, Cassidy R Prince, Letian Wu, Isabella N Lin, Katrina Callan, Heather A Feaga |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2025-04-01
|
| Series: | PLoS Genetics |
| Online Access: | https://doi.org/10.1371/journal.pgen.1011633 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
RNA-binding protein YebC enhances translation of proline-rich amino acid stretches in bacteria
by: Dmitriy Ignatov, et al.
Published: (2025-07-01) -
The ribosome-associated quality control pathway supports survival in the absence of non-stop ribosome rescue factors
by: Katrina Callan, et al.
Published: (2024-12-01) -
E3 ubiquitin ligase RNF10 promotes dissociation of stalled ribosomes and responds to ribosomal subunit imbalance
by: Janina A. Lehmann, et al.
Published: (2024-11-01) -
Ubiquitination of stalled ribosomes enables mRNA decay via HBS-1 and NONU-1 in vivo.
by: Parissa C Monem, et al.
Published: (2023-01-01) -
DNA Sensor ABCF1 Phase Separates With cccDNA to Inhibit Hepatitis B Virus Replication
by: Caiyue Ren, et al.
Published: (2024-12-01)