An on-chip deformability checker demonstrates that the severity of iron deficiency is associated with increased deformability of red blood cells

An on-chip deformability checker demonstrates that the severity of iron deficiency is associated with increased deformability of red blood cells

Abstract The deformability of red blood cells (RBCs) is essential for peripheral circulation and RBC survival and is reportedly altered in several diseases. However, its detail in iron-deficiency (ID) anemia remains poorly understood. We investigated the association between ID and RBC deformability...

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Bibliographic Details
Main Authors: Kenji Kajitani, Tomohito Ohtani, Rie Higuchi, Misato Chimura, Fusako Sera, Chia-Hung Dylan Tsai, Yasutaka Ueda, Jun-ichi Nishimura, Yasushi Sakata
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Scientific Reports
Subjects:
Deformability
Iron deficiency
Red blood cell
Morphology
Ferritin
Online Access:https://doi.org/10.1038/s41598-025-05483-2
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