A meta-analysis of the association between preoperative magnetic resonance imaging and surgical outcomes in newly diagnosed breast cancer
Introduction The use of preoperative magnetic resonance imaging (MRI) in newly diagnosed breast cancer has been increasing. However, the value of MRI applied to women with newly diagnosed breast cancer remains controversial. Therefore, this study focused on the association between preoperative MRI a...
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| Language: | English |
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Termedia Publishing House
2021-04-01
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| Series: | Archives of Medical Science |
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| Online Access: | https://www.archivesofmedicalscience.com/A-meta-analysis-of-the-association-between-preoperative-magnetic-resonance-imaging,120995,0,2.html |
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| author | Li-Li Xie Zhi-Hong Xu Deng-Hui Wei Chun-Sen Xu |
| author_facet | Li-Li Xie Zhi-Hong Xu Deng-Hui Wei Chun-Sen Xu |
| author_sort | Li-Li Xie |
| collection | DOAJ |
| description | Introduction
The use of preoperative magnetic resonance imaging (MRI) in newly diagnosed breast cancer has been increasing. However, the value of MRI applied to women with newly diagnosed breast cancer remains controversial. Therefore, this study focused on the association between preoperative MRI and surgical outcomes, which include mastectomy rate, breast conservation rate, and re-excision rate.
Material and methods
A systematic literature search was performed by the Wanfang, VIP (Chinese biomedical databases), PubMed, Cochrane Library, and Embase, databases. The keywords were “breast cancer”, “magnetic resonance imaging”, “mastectomy rate”, “re-excision rate”, and “breast conservation rate”. A random-effects model was used to estimate the proportion of women with various outcomes in the MRI group versus the non-MRI group. The odds ratio (OR) for each surgical outcome was calculated.
Results
4 RCTs (randomized controlled trials) met the eligibility criteria that included a total of 2312 patients with breast cancer. The analysis results of the MRI group versus the non-MRI group were as follows: mastectomy rate of 15% versus 10%, OR = 2.01, 95% CI: 0.79–5.11, p = 0.14; breast conservation rate 84% versus 89%, OR = 0.58, 95% CI: 0.29–1.17, p = 0.13; re-excision rate 17% versus 19%, OR = 0.76, 95% CI: 0.37–1.54, p = 0.45.
Conclusions
There was no significant association between preoperative MRI and surgical outcomes. This study suggested that the use of preoperative MRI should be selective. The results showed that the application of preoperative MRI did not improve the prognosis of breast cancer patients. More randomized trials are needed for further study due to limited randomized trials. |
| format | Article |
| id | doaj-art-6ced4d6e6ee84cedaf32803b4d8e3796 |
| institution | Kabale University |
| issn | 1734-1922 1896-9151 |
| language | English |
| publishDate | 2021-04-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Archives of Medical Science |
| spelling | doaj-art-6ced4d6e6ee84cedaf32803b4d8e37962025-01-27T10:44:31ZengTermedia Publishing HouseArchives of Medical Science1734-19221896-91512021-04-012051597160310.5114/aoms/120995120995A meta-analysis of the association between preoperative magnetic resonance imaging and surgical outcomes in newly diagnosed breast cancerLi-Li Xie0Zhi-Hong Xu1Deng-Hui Wei2Chun-Sen Xu3Fujian Medical University Union Hospital, Fuzhou, Fujian Province, ChinaFujian Medical University Union Hospital, Fuzhou, Fujian Province, ChinaFujian Medical University Union Hospital, Fuzhou, Fujian Province, ChinaFujian Medical University Union Hospital, Fuzhou, Fujian Province, ChinaIntroduction The use of preoperative magnetic resonance imaging (MRI) in newly diagnosed breast cancer has been increasing. However, the value of MRI applied to women with newly diagnosed breast cancer remains controversial. Therefore, this study focused on the association between preoperative MRI and surgical outcomes, which include mastectomy rate, breast conservation rate, and re-excision rate. Material and methods A systematic literature search was performed by the Wanfang, VIP (Chinese biomedical databases), PubMed, Cochrane Library, and Embase, databases. The keywords were “breast cancer”, “magnetic resonance imaging”, “mastectomy rate”, “re-excision rate”, and “breast conservation rate”. A random-effects model was used to estimate the proportion of women with various outcomes in the MRI group versus the non-MRI group. The odds ratio (OR) for each surgical outcome was calculated. Results 4 RCTs (randomized controlled trials) met the eligibility criteria that included a total of 2312 patients with breast cancer. The analysis results of the MRI group versus the non-MRI group were as follows: mastectomy rate of 15% versus 10%, OR = 2.01, 95% CI: 0.79–5.11, p = 0.14; breast conservation rate 84% versus 89%, OR = 0.58, 95% CI: 0.29–1.17, p = 0.13; re-excision rate 17% versus 19%, OR = 0.76, 95% CI: 0.37–1.54, p = 0.45. Conclusions There was no significant association between preoperative MRI and surgical outcomes. This study suggested that the use of preoperative MRI should be selective. The results showed that the application of preoperative MRI did not improve the prognosis of breast cancer patients. More randomized trials are needed for further study due to limited randomized trials.https://www.archivesofmedicalscience.com/A-meta-analysis-of-the-association-between-preoperative-magnetic-resonance-imaging,120995,0,2.htmlmagnetic resonance imagingbreast cancermastectomy ratebreast conservation ratere-excision ratemeta-analysis |
| spellingShingle | Li-Li Xie Zhi-Hong Xu Deng-Hui Wei Chun-Sen Xu A meta-analysis of the association between preoperative magnetic resonance imaging and surgical outcomes in newly diagnosed breast cancer Archives of Medical Science magnetic resonance imaging breast cancer mastectomy rate breast conservation rate re-excision rate meta-analysis |
| title | A meta-analysis of the association between preoperative magnetic resonance imaging and surgical outcomes in newly diagnosed breast cancer |
| title_full | A meta-analysis of the association between preoperative magnetic resonance imaging and surgical outcomes in newly diagnosed breast cancer |
| title_fullStr | A meta-analysis of the association between preoperative magnetic resonance imaging and surgical outcomes in newly diagnosed breast cancer |
| title_full_unstemmed | A meta-analysis of the association between preoperative magnetic resonance imaging and surgical outcomes in newly diagnosed breast cancer |
| title_short | A meta-analysis of the association between preoperative magnetic resonance imaging and surgical outcomes in newly diagnosed breast cancer |
| title_sort | meta analysis of the association between preoperative magnetic resonance imaging and surgical outcomes in newly diagnosed breast cancer |
| topic | magnetic resonance imaging breast cancer mastectomy rate breast conservation rate re-excision rate meta-analysis |
| url | https://www.archivesofmedicalscience.com/A-meta-analysis-of-the-association-between-preoperative-magnetic-resonance-imaging,120995,0,2.html |
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