Recent advances of photodiagnosis and treatment for head and neck squamous cell carcinoma
Head and neck squamous cell carcinoma (HNSCC) are the most common type of head and neck tumor that severely threatens human health due to its highly aggressive nature and susceptibility to distant metastasis. The diagnosis of HNSCC currently relies on biopsy and histopathological examination of susp...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-02-01
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| Series: | Neoplasia: An International Journal for Oncology Research |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1476558624001593 |
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| author | Yining Zhang Zhenfang Li Chengchi Zhang Chengying Shao Yanting Duan Guowan Zheng Yu Cai Minghua Ge Jiajie Xu |
| author_facet | Yining Zhang Zhenfang Li Chengchi Zhang Chengying Shao Yanting Duan Guowan Zheng Yu Cai Minghua Ge Jiajie Xu |
| author_sort | Yining Zhang |
| collection | DOAJ |
| description | Head and neck squamous cell carcinoma (HNSCC) are the most common type of head and neck tumor that severely threatens human health due to its highly aggressive nature and susceptibility to distant metastasis. The diagnosis of HNSCC currently relies on biopsy and histopathological examination of suspicious lesions. However, the early mucosal changes are subtle and difficult to detect by conventional oral examination. As for treatment, surgery is still the primary treatment modality. Due to the complex anatomy and the lack of intraoperative modalities to accurately determine the incision margins, surgeons are in a dilemma between extensive tumor removal and improving the quality of patient survival. As more knowledge is gained about HNSCC, the increasing recognition of the value of optical imaging has been emphasized. Optical technology offers distinctive possibilities for early preoperative diagnosis, intraoperative real-time visualization of tumor margins, sentinel lymph node biopsies, phototherapy. Fluorescence imaging, narrow-band imaging, Raman spectroscopy, optical coherence tomography, hyperspectral imaging, and photoacoustic imaging have been reported for imaging HNSCC. This article provides a comprehensive overview of the fundamental principles and clinical applications of optical imaging in the diagnosis and treatment of HNSCC, focusing on identifying its strengths and limitations to facilitate advancements in this field. |
| format | Article |
| id | doaj-art-6cec5d0536ea4b4c9ee01536900e72d1 |
| institution | Kabale University |
| issn | 1476-5586 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Neoplasia: An International Journal for Oncology Research |
| spelling | doaj-art-6cec5d0536ea4b4c9ee01536900e72d12025-02-03T04:16:35ZengElsevierNeoplasia: An International Journal for Oncology Research1476-55862025-02-0160101118Recent advances of photodiagnosis and treatment for head and neck squamous cell carcinomaYining Zhang0Zhenfang Li1Chengchi Zhang2Chengying Shao3Yanting Duan4Guowan Zheng5Yu Cai6Minghua Ge7Jiajie Xu8Otolaryngology & Head and Neck Center, Cancer Center, Department of Head and Neck Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou 310014, Zhejiang, China; Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou 310053, ChinaOtolaryngology & Head and Neck Center, Cancer Center, Department of Head and Neck Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou 310014, Zhejiang, ChinaOtolaryngology & Head and Neck Center, Cancer Center, Department of Head and Neck Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou 310014, Zhejiang, China; Zhejiang University of Technology, Hangzhou 310023, ChinaOtolaryngology & Head and Neck Center, Cancer Center, Department of Head and Neck Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou 310014, Zhejiang, China; Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou 310053, ChinaZhejiang Provincial Clinical Research Center for Head & Neck Cancer, Hangzhou 310014, China; Zhejiang Key Laboratory of Precision Medicine Research on Head & Neck Cancer, Hangzhou 310014, ChinaZhejiang Provincial Clinical Research Center for Head & Neck Cancer, Hangzhou 310014, China; Zhejiang Key Laboratory of Precision Medicine Research on Head & Neck Cancer, Hangzhou 310014, ChinaDepartment of Rehabilitation Medicine, Center for Rehabilitation Medicine, Rehabilitation & Sports Medicine Research Institute of Zhejiang Province, Cancer Center, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang 310014, China; Corresponding authors.Otolaryngology & Head and Neck Center, Cancer Center, Department of Head and Neck Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou 310014, Zhejiang, China; Zhejiang Provincial Clinical Research Center for Head & Neck Cancer, Hangzhou 310014, China; Zhejiang Key Laboratory of Precision Medicine Research on Head & Neck Cancer, Hangzhou 310014, China; Corresponding authors.Otolaryngology & Head and Neck Center, Cancer Center, Department of Head and Neck Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou 310014, Zhejiang, China; Zhejiang Provincial Clinical Research Center for Head & Neck Cancer, Hangzhou 310014, China; Zhejiang Key Laboratory of Precision Medicine Research on Head & Neck Cancer, Hangzhou 310014, China; Corresponding authors.Head and neck squamous cell carcinoma (HNSCC) are the most common type of head and neck tumor that severely threatens human health due to its highly aggressive nature and susceptibility to distant metastasis. The diagnosis of HNSCC currently relies on biopsy and histopathological examination of suspicious lesions. However, the early mucosal changes are subtle and difficult to detect by conventional oral examination. As for treatment, surgery is still the primary treatment modality. Due to the complex anatomy and the lack of intraoperative modalities to accurately determine the incision margins, surgeons are in a dilemma between extensive tumor removal and improving the quality of patient survival. As more knowledge is gained about HNSCC, the increasing recognition of the value of optical imaging has been emphasized. Optical technology offers distinctive possibilities for early preoperative diagnosis, intraoperative real-time visualization of tumor margins, sentinel lymph node biopsies, phototherapy. Fluorescence imaging, narrow-band imaging, Raman spectroscopy, optical coherence tomography, hyperspectral imaging, and photoacoustic imaging have been reported for imaging HNSCC. This article provides a comprehensive overview of the fundamental principles and clinical applications of optical imaging in the diagnosis and treatment of HNSCC, focusing on identifying its strengths and limitations to facilitate advancements in this field.http://www.sciencedirect.com/science/article/pii/S1476558624001593Head and neck squamous cell carcinomaOptical imagingPhotodynamic therapyPhotothermal therapyTheranostics |
| spellingShingle | Yining Zhang Zhenfang Li Chengchi Zhang Chengying Shao Yanting Duan Guowan Zheng Yu Cai Minghua Ge Jiajie Xu Recent advances of photodiagnosis and treatment for head and neck squamous cell carcinoma Neoplasia: An International Journal for Oncology Research Head and neck squamous cell carcinoma Optical imaging Photodynamic therapy Photothermal therapy Theranostics |
| title | Recent advances of photodiagnosis and treatment for head and neck squamous cell carcinoma |
| title_full | Recent advances of photodiagnosis and treatment for head and neck squamous cell carcinoma |
| title_fullStr | Recent advances of photodiagnosis and treatment for head and neck squamous cell carcinoma |
| title_full_unstemmed | Recent advances of photodiagnosis and treatment for head and neck squamous cell carcinoma |
| title_short | Recent advances of photodiagnosis and treatment for head and neck squamous cell carcinoma |
| title_sort | recent advances of photodiagnosis and treatment for head and neck squamous cell carcinoma |
| topic | Head and neck squamous cell carcinoma Optical imaging Photodynamic therapy Photothermal therapy Theranostics |
| url | http://www.sciencedirect.com/science/article/pii/S1476558624001593 |
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