USP35 promotes hepatocellular carcinoma proliferation through GASC1-mediated ROCK2 upregulation

USP35 promotes hepatocellular carcinoma proliferation through GASC1-mediated ROCK2 upregulation

Ubiquitin-specific protease 35 (USP35) regulates the oncogenic process of various cancers by stabilizing target proteins through deubiquitination. However, the function of USP35 in hepatocellular carcinoma (HCC) remains unclear. Our results demonstrated that USP35 was significantly over-expressed in...

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Bibliographic Details
Main Authors:	Gen Chen, Yong Shi, Shuaimin Zhang, Xiaofang Zhang, Guohui Li, Chenghang Jiang
Format:	Article
Language:	English
Published:	Elsevier 2025-08-01
Series:	Translational Oncology
Subjects:	Usp35 Gasc1 Rock2 Hepatocellular carcinoma Proliferation
Online Access:	http://www.sciencedirect.com/science/article/pii/S1936523325001615
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