(1→3)-β-D-glucan in patients with pulmonary aspergilloma
To elucidate the role of (1→3)-β-D-glucan in pulmonary aspergilloma, serum concentrations of (1→3)-β-D-glucan were measured repeatedly for as long as 10 months in eight patients. In four patients with inactive disease, concentrations of (1→3)-β-D-glucan were in the normal range.The concentrations of...
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Wiley
1997-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1080/09629359791631 |
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author | Kazumi Yuasa Hajime Goto |
author_facet | Kazumi Yuasa Hajime Goto |
author_sort | Kazumi Yuasa |
collection | DOAJ |
description | To elucidate the role of (1→3)-β-D-glucan in pulmonary aspergilloma, serum concentrations of (1→3)-β-D-glucan were measured repeatedly for as long as 10 months in eight patients. In four patients with inactive disease, concentrations of (1→3)-β-D-glucan were in the normal range.The concentrations of (1→3)-β-D-glucan increased in two patients, although the disease was inactive. This increase might show the earliest stage of the invasive process of the disease. In two other patients with active disease, (1→3)-β-D-glucan increased. Other parameters, such as galactomannan, immunodiffusion and a radio-allergosorbent test, as well as inflammatory m arkers such as C-reactive protein and the leukocyte count, did not show any consistent tendency in regard to the activity of the disease. Thus, a (1→3)-β-D-glucan assay may add valuable data for evaluating the disease activity and understanding the disease process of pulmonary aspergilloma. |
format | Article |
id | doaj-art-6c963fc11edb4891bd5bddf3b412eb99 |
institution | Kabale University |
issn | 0962-9351 1466-1861 |
language | English |
publishDate | 1997-01-01 |
publisher | Wiley |
record_format | Article |
series | Mediators of Inflammation |
spelling | doaj-art-6c963fc11edb4891bd5bddf3b412eb992025-02-03T05:43:37ZengWileyMediators of Inflammation0962-93511466-18611997-01-016428528710.1080/09629359791631(1→3)-β-D-glucan in patients with pulmonary aspergillomaKazumi Yuasa0Hajime Goto1Department of Pulmonary Disease, Tokyo Metropolitan Komagome General Hospital, 3-18-22 Honkomagome, Bunkyou-ku, Tokyo 113, JapanDepartment of Pulmonary Disease, Tokyo Metropolitan Komagome General Hospital, 3-18-22 Honkomagome, Bunkyou-ku, Tokyo 113, JapanTo elucidate the role of (1→3)-β-D-glucan in pulmonary aspergilloma, serum concentrations of (1→3)-β-D-glucan were measured repeatedly for as long as 10 months in eight patients. In four patients with inactive disease, concentrations of (1→3)-β-D-glucan were in the normal range.The concentrations of (1→3)-β-D-glucan increased in two patients, although the disease was inactive. This increase might show the earliest stage of the invasive process of the disease. In two other patients with active disease, (1→3)-β-D-glucan increased. Other parameters, such as galactomannan, immunodiffusion and a radio-allergosorbent test, as well as inflammatory m arkers such as C-reactive protein and the leukocyte count, did not show any consistent tendency in regard to the activity of the disease. Thus, a (1→3)-β-D-glucan assay may add valuable data for evaluating the disease activity and understanding the disease process of pulmonary aspergilloma.http://dx.doi.org/10.1080/09629359791631 |
spellingShingle | Kazumi Yuasa Hajime Goto (1→3)-β-D-glucan in patients with pulmonary aspergilloma Mediators of Inflammation |
title | (1→3)-β-D-glucan in patients with pulmonary aspergilloma |
title_full | (1→3)-β-D-glucan in patients with pulmonary aspergilloma |
title_fullStr | (1→3)-β-D-glucan in patients with pulmonary aspergilloma |
title_full_unstemmed | (1→3)-β-D-glucan in patients with pulmonary aspergilloma |
title_short | (1→3)-β-D-glucan in patients with pulmonary aspergilloma |
title_sort | 1 3 β d glucan in patients with pulmonary aspergilloma |
url | http://dx.doi.org/10.1080/09629359791631 |
work_keys_str_mv | AT kazumiyuasa 13bdglucaninpatientswithpulmonaryaspergilloma AT hajimegoto 13bdglucaninpatientswithpulmonaryaspergilloma |