Laryngeal Inflammatory Pseudotumour Secondary to Mycobacterium kansasii

Background. Inflammatory pseudotumours (IPT) are rare benign tumours characterised by spindle-shaped histiocyte proliferation often mimicking a soft tissue sarcoma. They can occur in different parts of the body and various aetiological factors have been proposed. To our knowledge this is the first c...

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Main Authors: Saif Al-Zahid, Tanwen Wright, Philip Reece
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Pathology
Online Access:http://dx.doi.org/10.1155/2018/9356243
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author Saif Al-Zahid
Tanwen Wright
Philip Reece
author_facet Saif Al-Zahid
Tanwen Wright
Philip Reece
author_sort Saif Al-Zahid
collection DOAJ
description Background. Inflammatory pseudotumours (IPT) are rare benign tumours characterised by spindle-shaped histiocyte proliferation often mimicking a soft tissue sarcoma. They can occur in different parts of the body and various aetiological factors have been proposed. To our knowledge this is the first case report of IPT of the larynx caused by mycobacterial disease. Case Report. We report a case of IPT of the larynx in an immunocompromised 81-year-old lady presenting with stridor and dysphagia with known disseminated Mycobacterium kansasii of the lungs. Conclusion. This case demonstrates both the clinical and histological difficulties in making the diagnosis of IPT. A high index of suspicion is needed, and the importance of a multidisciplinary approach in the work-up, diagnosis, and management is highlighted.
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institution Kabale University
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series Case Reports in Pathology
spelling doaj-art-6c8359d5f8274e8e8ee52dadf8c77fde2025-02-03T01:09:41ZengWileyCase Reports in Pathology2090-67812090-679X2018-01-01201810.1155/2018/93562439356243Laryngeal Inflammatory Pseudotumour Secondary to Mycobacterium kansasiiSaif Al-Zahid0Tanwen Wright1Philip Reece2University Hospitals Bristol NHS Foundation Trust, UKDepartment of Histopathology, Torbay Hospital, UKDepartment of Otolaryngology, Torbay Hospital, UKBackground. Inflammatory pseudotumours (IPT) are rare benign tumours characterised by spindle-shaped histiocyte proliferation often mimicking a soft tissue sarcoma. They can occur in different parts of the body and various aetiological factors have been proposed. To our knowledge this is the first case report of IPT of the larynx caused by mycobacterial disease. Case Report. We report a case of IPT of the larynx in an immunocompromised 81-year-old lady presenting with stridor and dysphagia with known disseminated Mycobacterium kansasii of the lungs. Conclusion. This case demonstrates both the clinical and histological difficulties in making the diagnosis of IPT. A high index of suspicion is needed, and the importance of a multidisciplinary approach in the work-up, diagnosis, and management is highlighted.http://dx.doi.org/10.1155/2018/9356243
spellingShingle Saif Al-Zahid
Tanwen Wright
Philip Reece
Laryngeal Inflammatory Pseudotumour Secondary to Mycobacterium kansasii
Case Reports in Pathology
title Laryngeal Inflammatory Pseudotumour Secondary to Mycobacterium kansasii
title_full Laryngeal Inflammatory Pseudotumour Secondary to Mycobacterium kansasii
title_fullStr Laryngeal Inflammatory Pseudotumour Secondary to Mycobacterium kansasii
title_full_unstemmed Laryngeal Inflammatory Pseudotumour Secondary to Mycobacterium kansasii
title_short Laryngeal Inflammatory Pseudotumour Secondary to Mycobacterium kansasii
title_sort laryngeal inflammatory pseudotumour secondary to mycobacterium kansasii
url http://dx.doi.org/10.1155/2018/9356243
work_keys_str_mv AT saifalzahid laryngealinflammatorypseudotumoursecondarytomycobacteriumkansasii
AT tanwenwright laryngealinflammatorypseudotumoursecondarytomycobacteriumkansasii
AT philipreece laryngealinflammatorypseudotumoursecondarytomycobacteriumkansasii