Low-Vacuum Quadrupole Mass Filter Using a Drift Gas

Performing mass spectrometry in a low-vacuum environment can markedly reduce the cost, size, and power consumption of instrumentation by reducing the workload of the pumping system. Under a low-vacuum environment, ions in a quadrupole mass filter do not have sufficient kinetic energy in the axial di...

Full description

Saved in:
Bibliographic Details
Main Authors: Peihe Jiang, Zhanfeng Zhao
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:International Journal of Analytical Chemistry
Online Access:http://dx.doi.org/10.1155/2020/8883490
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832567941771558912
author Peihe Jiang
Zhanfeng Zhao
author_facet Peihe Jiang
Zhanfeng Zhao
author_sort Peihe Jiang
collection DOAJ
description Performing mass spectrometry in a low-vacuum environment can markedly reduce the cost, size, and power consumption of instrumentation by reducing the workload of the pumping system. Under a low-vacuum environment, ions in a quadrupole mass filter do not have sufficient kinetic energy in the axial direction to reach the detector for mass analysis. To resolve this problem and develop a mass spectrometer suitable for a low-vacuum environment, a mass analysis method is proposed where a drift gas is used to supply energy to the ions. A simulation model was constructed in COMSOL Multiphysics, and a simple experimental device was built to validate the proposed method. The simulation results showed that this method effectively solves these problems, and the obtained spectral peak was superior to that without drift gas flow regarding spectral peak intensity and width. The experimental results showed that the proposed method separated ions with different mass-to-charge ratios at a pressure of 20 Pa. This work provides a theoretical foundation for the development of low-vacuum mass spectrometry, which will promote portability, provide a lower threshold of use, and expand the fields of application for mass spectrometers.
format Article
id doaj-art-6c71931a1436453299b0c7d060209840
institution Kabale University
issn 1687-8760
1687-8779
language English
publishDate 2020-01-01
publisher Wiley
record_format Article
series International Journal of Analytical Chemistry
spelling doaj-art-6c71931a1436453299b0c7d0602098402025-02-03T01:00:13ZengWileyInternational Journal of Analytical Chemistry1687-87601687-87792020-01-01202010.1155/2020/88834908883490Low-Vacuum Quadrupole Mass Filter Using a Drift GasPeihe Jiang0Zhanfeng Zhao1Shandong Fisherman Information Technology Co., Ltd., Weihai 264200, ChinaSchool of Information and Electrical Engineering, Harbin Institute of Technology, Harbin 150001, ChinaPerforming mass spectrometry in a low-vacuum environment can markedly reduce the cost, size, and power consumption of instrumentation by reducing the workload of the pumping system. Under a low-vacuum environment, ions in a quadrupole mass filter do not have sufficient kinetic energy in the axial direction to reach the detector for mass analysis. To resolve this problem and develop a mass spectrometer suitable for a low-vacuum environment, a mass analysis method is proposed where a drift gas is used to supply energy to the ions. A simulation model was constructed in COMSOL Multiphysics, and a simple experimental device was built to validate the proposed method. The simulation results showed that this method effectively solves these problems, and the obtained spectral peak was superior to that without drift gas flow regarding spectral peak intensity and width. The experimental results showed that the proposed method separated ions with different mass-to-charge ratios at a pressure of 20 Pa. This work provides a theoretical foundation for the development of low-vacuum mass spectrometry, which will promote portability, provide a lower threshold of use, and expand the fields of application for mass spectrometers.http://dx.doi.org/10.1155/2020/8883490
spellingShingle Peihe Jiang
Zhanfeng Zhao
Low-Vacuum Quadrupole Mass Filter Using a Drift Gas
International Journal of Analytical Chemistry
title Low-Vacuum Quadrupole Mass Filter Using a Drift Gas
title_full Low-Vacuum Quadrupole Mass Filter Using a Drift Gas
title_fullStr Low-Vacuum Quadrupole Mass Filter Using a Drift Gas
title_full_unstemmed Low-Vacuum Quadrupole Mass Filter Using a Drift Gas
title_short Low-Vacuum Quadrupole Mass Filter Using a Drift Gas
title_sort low vacuum quadrupole mass filter using a drift gas
url http://dx.doi.org/10.1155/2020/8883490
work_keys_str_mv AT peihejiang lowvacuumquadrupolemassfilterusingadriftgas
AT zhanfengzhao lowvacuumquadrupolemassfilterusingadriftgas