Sebaceous vs. lipid-rich carcinoma of the breast. Clinicopathological characteristics and correlations – a report of two cases and a literature review

Primary sebaceous and lipid-rich carcinomas are extremely rare. Sebaceous carcinoma cells are large and oval with light, partially vacuolated cytoplasm. The second population consists of cells located mainly on the peripheral parts of tumour beaches. Those cells are of smaller calibre and are fusifo...

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Main Authors: Nikola Živković, Ana Cvetanović, Miloš Kostić, Maja Jovičić Milentijević, Miodrag Djordjević, Tijana Denčić, Julija Cvetković, Mirjana Ćuk
Format: Article
Language:English
Published: Termedia Publishing House 2024-09-01
Series:Polish Journal of Pathology
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Online Access:https://www.termedia.pl/Sebaceous-vs-lipid-rich-carcinoma-of-the-breast-Clinicopathological-characteristics-and-correlations-a-report-of-two-cases-and-a-literature-review,55,54796,1,1.html
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Summary:Primary sebaceous and lipid-rich carcinomas are extremely rare. Sebaceous carcinoma cells are large and oval with light, partially vacuolated cytoplasm. The second population consists of cells located mainly on the peripheral parts of tumour beaches. Those cells are of smaller calibre and are fusiform in appearance. Lipid- rich carcinoma is made up of multiple cell populations. The predominant cell type is with a distinctly light, vacuolated, and partially optically clear cytoplasm. Pathohistological analysis may be overlapping. On one side there is a tumour with a relatively excellent prognosis, and on the other, a highly aggressive carcinoma with a tendency for early metastases.
ISSN:1233-9687
2084-9869