Study of Antibacterial Activity and Energy of Formation of Peptide Ligand Complexes With Hybrid Antibiotics Vancomycin-Azithromycin and Eremomycin-Azithromycin

Study of Antibacterial Activity and Energy of Formation of Peptide Ligand Complexes With Hybrid Antibiotics Vancomycin-Azithromycin and Eremomycin-Azithromycin

Antibacterial activity of hybrid antibiotics vancomycin-azithromycin (C11, C12-carbonate) and eremomycin-azitromycin (C11, C12-carbonate) was evaluated. Quantum chemical calculations of complexes of hybrid antibiotics with a model tripeptide ligand a, ε-di-Ac-L-Lys-D-Ala-D-Ala by the semi empirical...

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Bibliographic Details
Main Authors: E. E. Bykov, E. P. Mirchink, E. B. Isakova, E. N. Bychkova, E. N. Olsufyeva, A. N. Tevyashova
Format: Article
Language:Russian
Published: LLC "Publishing House OKI" 2020-05-01
Series:Антибиотики и Химиотерапия
Subjects:
vancomycin
eremomycin
azithromycin
hybrid antibiotics
antibacterial activity
antibiotic
ligand complex
quantum chemical calculations
semi empirical method pm6
Online Access:https://www.antibiotics-chemotherapy.ru/jour/article/view/14
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