Gal-3 activates Tyro3 to ameliorate ferroptosis of hippocampal neurons after traumatic brain injury

Gal-3 activates Tyro3 to ameliorate ferroptosis of hippocampal neurons after traumatic brain injury

Traumatic brain injury (TBI) leads to significant hippocampal neuronal loss, contributing to cognitive dysfunction. Our bioinformatics analysis of single-cell RNA sequencing data from hippocampal tissue following TBI revealed persistent neuronal loss and activation of ferroptosis-related pathways. N...

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Bibliographic Details
Main Authors: Xiao Zhang, Manrui Li, Yang Xu, Jingting Wu, Ruixuan Yuan, Yihan Sun, Xiaogang Chen, Meili Lv, Bo Jin, Xiameng Chen, Weibo Liang
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
MT: Bioinformatics
traumatic brain injury
hippocampal neuron
ferroptosis
Tyro3
Gal-3
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253124003202
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