How many doses and what type of antibiotic should be used as systemic antibiotic prophylaxis in primary hip and knee arthroplasty? A register-based study on 301,204 primary total and hemi- hip and total knee arthroplasties in Norway 2005–2023

How many doses and what type of antibiotic should be used as systemic antibiotic prophylaxis in primary hip and knee arthroplasty? A register-based study on 301,204 primary total and hemi- hip and total knee arthroplasties in Norway 2005–2023

Background and purpose: Guidelines for systemic antibiotic prophylaxis (SAP) in arthroplasty surgery vary worldwide from repeated doses to only 1 preoperatively. We aimed to investigate, primarily whether 4 doses reduced the risk of PJI compared with 1 to 3 doses, and secondarily if there was a dif...

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Main Authors: Olav Lutro, Marianne Bollestad Tjørhom, Tesfaye Hordofa Leta, Jan-Erik Gjertsen, Geir Hallan, Trond Bruun, Marianne Westberg, Tina Strømdal Wik, Christian Thomas Pollmann, Stein Håkon Lygre, Ove Furnes, Lars Engesæter, Håvard Dale
Format: Article
Language:English
Published: Medical Journals Sweden 2025-03-01
Series:Acta Orthopaedica
Subjects:
Hip
Implants
Infection
Knee
Online Access:https://actaorthop.org/actao/article/view/43003
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