Can invariant Natural Killer T cells drive B cell fate? a look at the humoral response

Can invariant Natural Killer T cells drive B cell fate? a look at the humoral response

Invariant Natural Killer T (NKT) cells represent a unique subset of innate-like T cells that express both NK cell and T cell receptors. These cells are rapidly activated by glycolipid antigens presented via CD1d molecules on antigen-presenting cells (APCs), including B cells, dendritic cells (DCs),...

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Bibliographic Details
Main Authors: Pablo A. Palacios, Álvaro Santibañez, Fernanda Aguirre-Muñoz, Cristián Gutiérrez-Vera, Valentina Niño de Zepeda-Carrizo, Martín Góngora-Pimentel, Marioly Müller, Mónica Cáceres, Alexis M. Kalergis, Leandro J. Carreño
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Immunology
Subjects:
iNKT cells
glycolipids
B cells
germinal center
class-switch recombination
humoral response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1505883/full
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