DETECTION SYSTEM OF A NEW-GENERATION BIOANALYTICAL DEVICE

We designed and manufactured a system for detection of antibodies/antigenes in biological fluids. This system records the kinetics of free immunodiffusion of fluorescent nanocomplexes inside the channels of a microfluid module of a new-generation bioanalytical device. The system consists of four par...

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Main Authors: E. V. Sysoev, A. K. Potashnikov, Y. V. Obidin, T. N. Goryachkovskaya, V. S. Bazin, V. M. Popik, S. E. Peltek, N. A. Kolchanov
Format: Article
Language:English
Published: Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders 2014-12-01
Series:Вавиловский журнал генетики и селекции
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Online Access:https://vavilov.elpub.ru/jour/article/view/84
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author E. V. Sysoev
A. K. Potashnikov
Y. V. Obidin
T. N. Goryachkovskaya
V. S. Bazin
V. M. Popik
S. E. Peltek
N. A. Kolchanov
author_facet E. V. Sysoev
A. K. Potashnikov
Y. V. Obidin
T. N. Goryachkovskaya
V. S. Bazin
V. M. Popik
S. E. Peltek
N. A. Kolchanov
author_sort E. V. Sysoev
collection DOAJ
description We designed and manufactured a system for detection of antibodies/antigenes in biological fluids. This system records the kinetics of free immunodiffusion of fluorescent nanocomplexes inside the channels of a microfluid module of a new-generation bioanalytical device. The system consists of four parallel excitation channels, a system for fluorescence detection, and an image-processing program. Antibody/antigen concentrations below 0,1 μg/ml can be detected in biological fluids.
format Article
id doaj-art-6c1526700c464bf0ac17c4f5a7643803
institution Kabale University
issn 2500-3259
language English
publishDate 2014-12-01
publisher Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders
record_format Article
series Вавиловский журнал генетики и селекции
spelling doaj-art-6c1526700c464bf0ac17c4f5a76438032025-02-01T09:57:59ZengSiberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and BreedersВавиловский журнал генетики и селекции2500-32592014-12-01164/185886568DETECTION SYSTEM OF A NEW-GENERATION BIOANALYTICAL DEVICEE. V. Sysoev0A. K. Potashnikov1Y. V. Obidin2T. N. Goryachkovskaya3V. S. Bazin4V. M. Popik5S. E. Peltek6N. A. Kolchanov7Technological Design Institute of Scientifi c Instrument Engineering SB RAS, Novosibirsk, RussiaTechnological Design Institute of Scientifi c Instrument Engineering SB RAS, Novosibirsk, RussiaTechnological Design Institute of Scientifi c Instrument Engineering SB RAS, Novosibirsk, RussiaInstitute of Cytology and Genetics SB RAS, Novosibirsk, RussiaTechnological Design Institute of Scientifi c Instrument Engineering SB RAS, Novosibirsk, RussiaBudker Institute of Nuclear Physics SB RAS, Novosibirsk, RussiaInstitute of Cytology and Genetics SB RAS, Novosibirsk, RussiaInstitute of Cytology and Genetics SB RAS, Novosibirsk, Russia Novosibirsk National Research State University, Novosibirsk, Russia National Research Centre «Kurchatov Institute», Moscow, RussiaWe designed and manufactured a system for detection of antibodies/antigenes in biological fluids. This system records the kinetics of free immunodiffusion of fluorescent nanocomplexes inside the channels of a microfluid module of a new-generation bioanalytical device. The system consists of four parallel excitation channels, a system for fluorescence detection, and an image-processing program. Antibody/antigen concentrations below 0,1 μg/ml can be detected in biological fluids.https://vavilov.elpub.ru/jour/article/view/84bioanalytical devicesbiosafetymicrofluid system
spellingShingle E. V. Sysoev
A. K. Potashnikov
Y. V. Obidin
T. N. Goryachkovskaya
V. S. Bazin
V. M. Popik
S. E. Peltek
N. A. Kolchanov
DETECTION SYSTEM OF A NEW-GENERATION BIOANALYTICAL DEVICE
Вавиловский журнал генетики и селекции
bioanalytical devices
biosafety
microfluid system
title DETECTION SYSTEM OF A NEW-GENERATION BIOANALYTICAL DEVICE
title_full DETECTION SYSTEM OF A NEW-GENERATION BIOANALYTICAL DEVICE
title_fullStr DETECTION SYSTEM OF A NEW-GENERATION BIOANALYTICAL DEVICE
title_full_unstemmed DETECTION SYSTEM OF A NEW-GENERATION BIOANALYTICAL DEVICE
title_short DETECTION SYSTEM OF A NEW-GENERATION BIOANALYTICAL DEVICE
title_sort detection system of a new generation bioanalytical device
topic bioanalytical devices
biosafety
microfluid system
url https://vavilov.elpub.ru/jour/article/view/84
work_keys_str_mv AT evsysoev detectionsystemofanewgenerationbioanalyticaldevice
AT akpotashnikov detectionsystemofanewgenerationbioanalyticaldevice
AT yvobidin detectionsystemofanewgenerationbioanalyticaldevice
AT tngoryachkovskaya detectionsystemofanewgenerationbioanalyticaldevice
AT vsbazin detectionsystemofanewgenerationbioanalyticaldevice
AT vmpopik detectionsystemofanewgenerationbioanalyticaldevice
AT sepeltek detectionsystemofanewgenerationbioanalyticaldevice
AT nakolchanov detectionsystemofanewgenerationbioanalyticaldevice