Safety and tolerability of intramuscular sotrovimab administered at different injection sites: results from the Phase 1 COSMIC study

Safety and tolerability of intramuscular sotrovimab administered at different injection sites: results from the Phase 1 COSMIC study

Monoclonal antibodies (mAbs) administered using intramuscular (IM) injections could offer a convenient and accessible therapeutic option. However, there is a paucity of data on IM tolerability by injection site to guide mAb development. This Phase 1, open-label trial randomized healthy adults to rec...

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Bibliographic Details
Main Authors: Jennifer Moore, Alicia Aylott, Wen-Hung Chen, Jerzy Daniluk, Ian A. Hawes, Sergio Parra, Prosenjit Sarkar, Yasmin Sanchez-Pearson, Megan Turner, Amanda Peppercorn, Andrew Skingsley
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:mAbs
Subjects:
COVID-19
injection-site reaction
intramuscular
monoclonal antibody
pain
patient-reported outcome
Online Access:https://www.tandfonline.com/doi/10.1080/19420862.2025.2456467
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