Verteporfin Photodynamic Therapy Combined with Intravitreal Ranibizumab for Polypoidal Choroidal Vasculopathy Controversy Concerning Long-Term Followup
Purpose. To show the long-term results of intravitreal ranibizumab combined with photodynamic therapy (PDT) for the treatment of polypoidal choroidal vasculopathy (PCV). Methods. We analyzed the progress of two patients for 36 and 58 months, respectively. We only used PDT for the treatment in the ar...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2012-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2012/897097 |
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| Summary: | Purpose. To show the long-term results of intravitreal ranibizumab combined with
photodynamic therapy (PDT) for the treatment of polypoidal choroidal vasculopathy (PCV). Methods. We analyzed the progress of two patients for 36 and 58 months, respectively. We only
used PDT for the treatment in the area of the active PCV or “hot spot” evident on the
indocyanine green angiography (ICGA). The spot size was chosen so as to cover only the
active neovascular lesion. We combined intravitreal ranibizumab with PDT when PCV
remained active without visible polyps in ICGA or without a response to PDT. Conclusion. Administration, as required, of verteporfin photodynamic therapy combined
with intravitreal ranibizumab is an effective treatment for symptomatic polypoidal
choroidal vasculopathy. These data need to be confirmed in large, prospective, and controlled
clinical trials which are randomized and carried out over a long period. |
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| ISSN: | 1687-9627 1687-9635 |