Radiation Degradation of β-Glucan Extracted from Brewer’s Yeast for Enhancing Growth Promotion and Immunostimulant Activities on Broilers
Water-soluble low molecular weight β-glucan (WSLMG) was successfully prepared via γ-irradiation of insoluble β-glucan extracted from brewer’s yeast cell walls. The WSLMG content in an irradiated sample increased as the irradiation dose increased. The WSLMGs with a molecular weight (Mw) of 49, 25, an...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | International Journal of Polymer Science |
| Online Access: | http://dx.doi.org/10.1155/2019/8901824 |
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| _version_ | 1832551676957949952 |
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| author | Nguyen Thanh Long Tran Le Truc Ha Hoang Nghia Son Le Quang Luan |
| author_facet | Nguyen Thanh Long Tran Le Truc Ha Hoang Nghia Son Le Quang Luan |
| author_sort | Nguyen Thanh Long |
| collection | DOAJ |
| description | Water-soluble low molecular weight β-glucan (WSLMG) was successfully prepared via γ-irradiation of insoluble β-glucan extracted from brewer’s yeast cell walls. The WSLMG content in an irradiated sample increased as the irradiation dose increased. The WSLMGs with a molecular weight (Mw) of 49, 25, and 11 kDa, obtained at correlative doses of 100, 200, and 300 kGy, respectively, were tested using growth promotion and immune stimulant effects in broilers. Supplementation with 500 ppm WSLMGs not only increased the survival rate (33.3%) and average body weight (40%) but also reduced the feed conversion rate (35.4%) in tested broilers. In addition, WSLMGs enhanced both nonspecific and specific immune components in the blood of supplemented broilers. The WSLMG with Mw ~25 kDa showed the highest effect on the growth performance and immunomodulatory capability in the immune systems of the tested broilers. In conclusion, this product demonstrates substantial promise as an immunostimulant and growth-promoting additive for poultry. |
| format | Article |
| id | doaj-art-6bea71abaed24df3bdebafd68e9d1c3d |
| institution | Kabale University |
| issn | 1687-9422 1687-9430 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Polymer Science |
| spelling | doaj-art-6bea71abaed24df3bdebafd68e9d1c3d2025-02-03T06:00:51ZengWileyInternational Journal of Polymer Science1687-94221687-94302019-01-01201910.1155/2019/89018248901824Radiation Degradation of β-Glucan Extracted from Brewer’s Yeast for Enhancing Growth Promotion and Immunostimulant Activities on BroilersNguyen Thanh Long0Tran Le Truc Ha1Hoang Nghia Son2Le Quang Luan3Nha Trang Vaccines and Biological Products Joint Stock Company, Khanh Hoa, VietnamNguyen Tat Thanh University, Ho Chi Minh City, VietnamInstitute of Tropical Biology, Vietnam Academy of Science and Technology, VietnamBiotechnology Center of Ho Chi Minh City, 2374, Highway 1, Trung My Tay Ward, District 12, Ho Chi Minh City, VietnamWater-soluble low molecular weight β-glucan (WSLMG) was successfully prepared via γ-irradiation of insoluble β-glucan extracted from brewer’s yeast cell walls. The WSLMG content in an irradiated sample increased as the irradiation dose increased. The WSLMGs with a molecular weight (Mw) of 49, 25, and 11 kDa, obtained at correlative doses of 100, 200, and 300 kGy, respectively, were tested using growth promotion and immune stimulant effects in broilers. Supplementation with 500 ppm WSLMGs not only increased the survival rate (33.3%) and average body weight (40%) but also reduced the feed conversion rate (35.4%) in tested broilers. In addition, WSLMGs enhanced both nonspecific and specific immune components in the blood of supplemented broilers. The WSLMG with Mw ~25 kDa showed the highest effect on the growth performance and immunomodulatory capability in the immune systems of the tested broilers. In conclusion, this product demonstrates substantial promise as an immunostimulant and growth-promoting additive for poultry.http://dx.doi.org/10.1155/2019/8901824 |
| spellingShingle | Nguyen Thanh Long Tran Le Truc Ha Hoang Nghia Son Le Quang Luan Radiation Degradation of β-Glucan Extracted from Brewer’s Yeast for Enhancing Growth Promotion and Immunostimulant Activities on Broilers International Journal of Polymer Science |
| title | Radiation Degradation of β-Glucan Extracted from Brewer’s Yeast for Enhancing Growth Promotion and Immunostimulant Activities on Broilers |
| title_full | Radiation Degradation of β-Glucan Extracted from Brewer’s Yeast for Enhancing Growth Promotion and Immunostimulant Activities on Broilers |
| title_fullStr | Radiation Degradation of β-Glucan Extracted from Brewer’s Yeast for Enhancing Growth Promotion and Immunostimulant Activities on Broilers |
| title_full_unstemmed | Radiation Degradation of β-Glucan Extracted from Brewer’s Yeast for Enhancing Growth Promotion and Immunostimulant Activities on Broilers |
| title_short | Radiation Degradation of β-Glucan Extracted from Brewer’s Yeast for Enhancing Growth Promotion and Immunostimulant Activities on Broilers |
| title_sort | radiation degradation of β glucan extracted from brewer s yeast for enhancing growth promotion and immunostimulant activities on broilers |
| url | http://dx.doi.org/10.1155/2019/8901824 |
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