The Critical Management of Spinal Cord Injury: A Narrative Review

Spinal cord injury (SCI) is defined as physical damage that alters the function and structure of the spinal cord. Traumatic causes, such as vehicle accidents, falls, and violence, account for 90% of SCI cases. Recent evidence suggests that early intensive care unit (ICU) monitoring improves patient...

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Main Authors: Emilio Moreno-González, Antonio Ibarra
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Clinics and Practice
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Online Access:https://www.mdpi.com/2039-7283/15/1/2
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author Emilio Moreno-González
Antonio Ibarra
author_facet Emilio Moreno-González
Antonio Ibarra
author_sort Emilio Moreno-González
collection DOAJ
description Spinal cord injury (SCI) is defined as physical damage that alters the function and structure of the spinal cord. Traumatic causes, such as vehicle accidents, falls, and violence, account for 90% of SCI cases. Recent evidence suggests that early intensive care unit (ICU) monitoring improves patient prognosis, highlighting the importance of prompt ICU admission and early decompression surgery. This review includes 50 publications selected based on specific criteria to gather evidence on the current management of SCI in acute settings. Pharmacological agents have been studied for their neuroprotective properties, offering hope for improved neurological outcomes. Several clinical trials are evaluating new pharmacological alternatives for SCI. In conclusion, the current management of acute SCI should focus on standardized treatments addressing ventilatory, cardiopulmonary, and hematologic complications, all of which directly impact long-term neurological and functional prognosis. New neuroprotective agents currently in clinical trials show promising results and should be further studied to determine their role in acute SCI management.
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spelling doaj-art-6bd0c483e9724b1fb440e1154b1cc1182025-01-24T13:27:39ZengMDPI AGClinics and Practice2039-72832024-12-01151210.3390/clinpract15010002The Critical Management of Spinal Cord Injury: A Narrative ReviewEmilio Moreno-González0Antonio Ibarra1Centro de Investigación de Ciencias de la Salud (CICSA), Facultad de Ciencias de la Salud, Universidad Anáhuac México Campus Norte, Huixquilucan CP 52786, Estado de México, MexicoCentro de Investigación de Ciencias de la Salud (CICSA), Facultad de Ciencias de la Salud, Universidad Anáhuac México Campus Norte, Huixquilucan CP 52786, Estado de México, MexicoSpinal cord injury (SCI) is defined as physical damage that alters the function and structure of the spinal cord. Traumatic causes, such as vehicle accidents, falls, and violence, account for 90% of SCI cases. Recent evidence suggests that early intensive care unit (ICU) monitoring improves patient prognosis, highlighting the importance of prompt ICU admission and early decompression surgery. This review includes 50 publications selected based on specific criteria to gather evidence on the current management of SCI in acute settings. Pharmacological agents have been studied for their neuroprotective properties, offering hope for improved neurological outcomes. Several clinical trials are evaluating new pharmacological alternatives for SCI. In conclusion, the current management of acute SCI should focus on standardized treatments addressing ventilatory, cardiopulmonary, and hematologic complications, all of which directly impact long-term neurological and functional prognosis. New neuroprotective agents currently in clinical trials show promising results and should be further studied to determine their role in acute SCI management.https://www.mdpi.com/2039-7283/15/1/2spinal cord injuryacute managementneuroprotection
spellingShingle Emilio Moreno-González
Antonio Ibarra
The Critical Management of Spinal Cord Injury: A Narrative Review
Clinics and Practice
spinal cord injury
acute management
neuroprotection
title The Critical Management of Spinal Cord Injury: A Narrative Review
title_full The Critical Management of Spinal Cord Injury: A Narrative Review
title_fullStr The Critical Management of Spinal Cord Injury: A Narrative Review
title_full_unstemmed The Critical Management of Spinal Cord Injury: A Narrative Review
title_short The Critical Management of Spinal Cord Injury: A Narrative Review
title_sort critical management of spinal cord injury a narrative review
topic spinal cord injury
acute management
neuroprotection
url https://www.mdpi.com/2039-7283/15/1/2
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