Molecular Iodine: A Powerful Catalyst for the Knoevenagel Condensation of Isatins with Malononitrile

Molecular iodine has been used as an efficient catalyst for an improved and rapid condensation of isatins with malononitrile in excellent yields. The significant features of the iodine-catalyzed Knoevenagel condensation are operational simplicity, inexpensive reagents, high yield of products, and th...

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Main Authors: Xiao Juan Yang, Yong Sen Zhang
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2013/543219
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author Xiao Juan Yang
Yong Sen Zhang
author_facet Xiao Juan Yang
Yong Sen Zhang
author_sort Xiao Juan Yang
collection DOAJ
description Molecular iodine has been used as an efficient catalyst for an improved and rapid condensation of isatins with malononitrile in excellent yields. The significant features of the iodine-catalyzed Knoevenagel condensation are operational simplicity, inexpensive reagents, high yield of products, and the use of nontoxic reagents.
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institution Kabale University
issn 2090-9063
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language English
publishDate 2013-01-01
publisher Wiley
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series Journal of Chemistry
spelling doaj-art-6bba475f3d644ec3aa4a1954fb3913912025-02-03T01:09:49ZengWileyJournal of Chemistry2090-90632090-90712013-01-01201310.1155/2013/543219543219Molecular Iodine: A Powerful Catalyst for the Knoevenagel Condensation of Isatins with MalononitrileXiao Juan Yang0Yong Sen Zhang1College of Chemistry and Chemical Engineering, Xinxiang University, Henan, Xinxiang 453003, ChinaThe Third Affiliated Hospital, Xinxiang Medical University, Henan, Xinxiang 45300, ChinaMolecular iodine has been used as an efficient catalyst for an improved and rapid condensation of isatins with malononitrile in excellent yields. The significant features of the iodine-catalyzed Knoevenagel condensation are operational simplicity, inexpensive reagents, high yield of products, and the use of nontoxic reagents.http://dx.doi.org/10.1155/2013/543219
spellingShingle Xiao Juan Yang
Yong Sen Zhang
Molecular Iodine: A Powerful Catalyst for the Knoevenagel Condensation of Isatins with Malononitrile
Journal of Chemistry
title Molecular Iodine: A Powerful Catalyst for the Knoevenagel Condensation of Isatins with Malononitrile
title_full Molecular Iodine: A Powerful Catalyst for the Knoevenagel Condensation of Isatins with Malononitrile
title_fullStr Molecular Iodine: A Powerful Catalyst for the Knoevenagel Condensation of Isatins with Malononitrile
title_full_unstemmed Molecular Iodine: A Powerful Catalyst for the Knoevenagel Condensation of Isatins with Malononitrile
title_short Molecular Iodine: A Powerful Catalyst for the Knoevenagel Condensation of Isatins with Malononitrile
title_sort molecular iodine a powerful catalyst for the knoevenagel condensation of isatins with malononitrile
url http://dx.doi.org/10.1155/2013/543219
work_keys_str_mv AT xiaojuanyang moleculariodineapowerfulcatalystfortheknoevenagelcondensationofisatinswithmalononitrile
AT yongsenzhang moleculariodineapowerfulcatalystfortheknoevenagelcondensationofisatinswithmalononitrile