Microbiota boost immunotherapy? A meta-analysis dives into fecal microbiota transplantation and immune checkpoint inhibitors

Microbiota boost immunotherapy? A meta-analysis dives into fecal microbiota transplantation and immune checkpoint inhibitors

Abstract Background Immune checkpoint inhibitors (ICIs) are a cornerstone of modern cancer treatment, but their effectiveness is limited. Fecal microbiota transplantation (FMT), which alters the gut microbiome, has shown promise in enhancing ICIs’ therapeutic effects. Methods We conducted a comprehe...

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Bibliographic Details
Main Authors: Anqi Lin, Lihaoyun Huang, Aimin Jiang, Lingxuan Zhu, Weiming Mou, Yu Li, Chunyan Zhang, Zaoqu Liu, Jian Zhang, Quan Cheng, Ting Wei, Peng Luo
Format: Article
Language:English
Published: BMC 2025-06-01
Series:BMC Medicine
Subjects:
Fecal microbiota transplantation
Immune checkpoint inhibitors
Clinical efficacy
Objective response rate
Adverse events
Online Access:https://doi.org/10.1186/s12916-025-04183-y
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