Renal Denervation Influences Angiotensin II Types 1 and 2 Receptors
The sympathetic and renin-angiotensin systems (RAS) are two critical regulatory systems in the kidney which affect renal hemodynamics and function. These two systems interact with each other so that angiotensin II (Ang II) has the presynaptic effect on the norepinephrine secretion. Another aspect of...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-01-01
|
| Series: | International Journal of Nephrology |
| Online Access: | http://dx.doi.org/10.1155/2022/8731357 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832562408764211200 |
|---|---|
| author | Hajaralsadat Hosseini-Dastgerdi Fatemeh Kharazmi Ali-Asghar Pourshanazari Mehdi Nematbakhsh |
| author_facet | Hajaralsadat Hosseini-Dastgerdi Fatemeh Kharazmi Ali-Asghar Pourshanazari Mehdi Nematbakhsh |
| author_sort | Hajaralsadat Hosseini-Dastgerdi |
| collection | DOAJ |
| description | The sympathetic and renin-angiotensin systems (RAS) are two critical regulatory systems in the kidney which affect renal hemodynamics and function. These two systems interact with each other so that angiotensin II (Ang II) has the presynaptic effect on the norepinephrine secretion. Another aspect of this interaction is that the sympathetic nervous system affects the function and expression of local RAS receptors, mainly Ang II receptors. Therefore, in many pathological conditions associated with an increased renal sympathetic tone, these receptors’ expression changes and renal denervation can normalize these changes and improve the diseases. It seems that the renal sympathectomy can alter Ang II receptors expression and the distribution of RAS receptors in the kidneys, which influence renal functions. |
| format | Article |
| id | doaj-art-6b9b61be8fef44dfad7a2ed1278e86f3 |
| institution | Kabale University |
| issn | 2090-2158 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Nephrology |
| spelling | doaj-art-6b9b61be8fef44dfad7a2ed1278e86f32025-02-03T01:22:40ZengWileyInternational Journal of Nephrology2090-21582022-01-01202210.1155/2022/8731357Renal Denervation Influences Angiotensin II Types 1 and 2 ReceptorsHajaralsadat Hosseini-Dastgerdi0Fatemeh Kharazmi1Ali-Asghar Pourshanazari2Mehdi Nematbakhsh3Water & Electrolytes Research Center and Department of PhysiologyWater & Electrolytes Research Center and Department of PhysiologyWater & Electrolytes Research Center and Department of PhysiologyWater & Electrolytes Research Center and Department of PhysiologyThe sympathetic and renin-angiotensin systems (RAS) are two critical regulatory systems in the kidney which affect renal hemodynamics and function. These two systems interact with each other so that angiotensin II (Ang II) has the presynaptic effect on the norepinephrine secretion. Another aspect of this interaction is that the sympathetic nervous system affects the function and expression of local RAS receptors, mainly Ang II receptors. Therefore, in many pathological conditions associated with an increased renal sympathetic tone, these receptors’ expression changes and renal denervation can normalize these changes and improve the diseases. It seems that the renal sympathectomy can alter Ang II receptors expression and the distribution of RAS receptors in the kidneys, which influence renal functions.http://dx.doi.org/10.1155/2022/8731357 |
| spellingShingle | Hajaralsadat Hosseini-Dastgerdi Fatemeh Kharazmi Ali-Asghar Pourshanazari Mehdi Nematbakhsh Renal Denervation Influences Angiotensin II Types 1 and 2 Receptors International Journal of Nephrology |
| title | Renal Denervation Influences Angiotensin II Types 1 and 2 Receptors |
| title_full | Renal Denervation Influences Angiotensin II Types 1 and 2 Receptors |
| title_fullStr | Renal Denervation Influences Angiotensin II Types 1 and 2 Receptors |
| title_full_unstemmed | Renal Denervation Influences Angiotensin II Types 1 and 2 Receptors |
| title_short | Renal Denervation Influences Angiotensin II Types 1 and 2 Receptors |
| title_sort | renal denervation influences angiotensin ii types 1 and 2 receptors |
| url | http://dx.doi.org/10.1155/2022/8731357 |
| work_keys_str_mv | AT hajaralsadathosseinidastgerdi renaldenervationinfluencesangiotensiniitypes1and2receptors AT fatemehkharazmi renaldenervationinfluencesangiotensiniitypes1and2receptors AT aliasgharpourshanazari renaldenervationinfluencesangiotensiniitypes1and2receptors AT mehdinematbakhsh renaldenervationinfluencesangiotensiniitypes1and2receptors |