Detecting amyloid and tau pathology in Parkinson’s disease, 4R-tauopathies and control subjects with plasma pTau217

Detecting amyloid and tau pathology in Parkinson’s disease, 4R-tauopathies and control subjects with plasma pTau217

IntroductionPlasma phospho-tau 217 (pTau217) is a biomarker for Alzheimer’s disease (AD) pathology, reflecting amyloid (Aβ) and tau burden, but its role in Parkinson disease (PD) and 4-repeat(4R)-tauopathies remains incompletely understood. We measured plasma pTau217 across the cognitive spectrum of...

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Main Authors: Giulia Musso, Eleonora Fiorenzato, Valentina Misenti, Simone Cauzzo, Roberta Biundo, Carmelo A. Fogliano, Giulia Bonato, Wassilios G. Meissner, Marta Campagnolo, Miryam Carecchio, Francesca Vianello, Andrea Guerra, Chiara Cosma, Annachiara Cagnin, Diego Cecchin, Martina Montagnana, Angelo Antonini
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Neurology
Subjects:
Parkinson’s disease
Progressive Supranuclear Palsy
mild cognitive impairment
pTau217
amyloid
tau
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2025.1638852/full
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