The Role of Gemcitabine in the Treatment of Cholangiocarcinoma and Gallbladder Cancer: A Systematic Review
BACKGROUND: Cholangiocarcinoma and gallbladder cancer are difficult to treat curatively. The treatment of choice is surgery, dependent on detection at a resectable stage. No chemotherapy or radiotherapy options have shown substantial activity. Gemcitabine has demonstrated response in similar cancers...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2005-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/2005/565479 |
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| _version_ | 1832562051912826880 |
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| author | Brian H Dingle R Bryan Rumble Melissa C Brouwers |
| author_facet | Brian H Dingle R Bryan Rumble Melissa C Brouwers |
| author_sort | Brian H Dingle |
| collection | DOAJ |
| description | BACKGROUND: Cholangiocarcinoma and gallbladder cancer are difficult to treat curatively. The treatment of choice is surgery, dependent on detection at a resectable stage. No chemotherapy or radiotherapy options have shown substantial activity. Gemcitabine has demonstrated response in similar cancers. Considering the lack of treatment options for cholangiocarcinoma and gallbladder cancer, a systematic review of the evidence on gemcitabine use for these indications was performed. |
| format | Article |
| id | doaj-art-6b723ab9a87740f39ce66a153ae38925 |
| institution | Kabale University |
| issn | 0835-7900 |
| language | English |
| publishDate | 2005-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology |
| spelling | doaj-art-6b723ab9a87740f39ce66a153ae389252025-02-03T01:23:32ZengWileyCanadian Journal of Gastroenterology0835-79002005-01-01191271171610.1155/2005/565479The Role of Gemcitabine in the Treatment of Cholangiocarcinoma and Gallbladder Cancer: A Systematic ReviewBrian H Dingle0R Bryan Rumble1Melissa C Brouwers2London Regional Cancer Program, Department of Oncology, University of Western Ontario, London, Ontario, CanadaCancer Care Ontario’s Program in Evidence-Based Care, Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, CanadaCancer Care Ontario’s Program in Evidence-Based Care, Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, CanadaBACKGROUND: Cholangiocarcinoma and gallbladder cancer are difficult to treat curatively. The treatment of choice is surgery, dependent on detection at a resectable stage. No chemotherapy or radiotherapy options have shown substantial activity. Gemcitabine has demonstrated response in similar cancers. Considering the lack of treatment options for cholangiocarcinoma and gallbladder cancer, a systematic review of the evidence on gemcitabine use for these indications was performed.http://dx.doi.org/10.1155/2005/565479 |
| spellingShingle | Brian H Dingle R Bryan Rumble Melissa C Brouwers The Role of Gemcitabine in the Treatment of Cholangiocarcinoma and Gallbladder Cancer: A Systematic Review Canadian Journal of Gastroenterology |
| title | The Role of Gemcitabine in the Treatment of Cholangiocarcinoma and Gallbladder Cancer: A Systematic Review |
| title_full | The Role of Gemcitabine in the Treatment of Cholangiocarcinoma and Gallbladder Cancer: A Systematic Review |
| title_fullStr | The Role of Gemcitabine in the Treatment of Cholangiocarcinoma and Gallbladder Cancer: A Systematic Review |
| title_full_unstemmed | The Role of Gemcitabine in the Treatment of Cholangiocarcinoma and Gallbladder Cancer: A Systematic Review |
| title_short | The Role of Gemcitabine in the Treatment of Cholangiocarcinoma and Gallbladder Cancer: A Systematic Review |
| title_sort | role of gemcitabine in the treatment of cholangiocarcinoma and gallbladder cancer a systematic review |
| url | http://dx.doi.org/10.1155/2005/565479 |
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