Effects of Consuming Pulsed UV Light-Treated <i>Pleurotus citrinopileatus</i> on Vitamin D Nutritional Status in Healthy Adults
Vitamin D, essential for growth and health, is often deficient in Taiwan despite abundant sunlight. Plant-derived vitamin D<sub>2</sub> (ergocalciferol) is bioavailable, environmentally friendly, and cost-effective. This study evaluated the efficacy of enhancing <i>Pleurotus citrin...
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MDPI AG
2025-01-01
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| author | Chih-Ching Hsu Chiao-Ming Chen Yu-Ming Ju Yu-Ching Wu Huei-Mei Hsieh Shu-Hui Yang Chien-Tien Su Te-Chao Fang Widiastuti Setyaningsih Sing-Chung Li |
| author_facet | Chih-Ching Hsu Chiao-Ming Chen Yu-Ming Ju Yu-Ching Wu Huei-Mei Hsieh Shu-Hui Yang Chien-Tien Su Te-Chao Fang Widiastuti Setyaningsih Sing-Chung Li |
| author_sort | Chih-Ching Hsu |
| collection | DOAJ |
| description | Vitamin D, essential for growth and health, is often deficient in Taiwan despite abundant sunlight. Plant-derived vitamin D<sub>2</sub> (ergocalciferol) is bioavailable, environmentally friendly, and cost-effective. This study evaluated the efficacy of enhancing <i>Pleurotus citrinopileatus</i> (PC) mushrooms’ vitamin D<sub>2</sub> content through pulsed ultraviolet (PUV) light and its impact on vitamin D status in humans. In a four-week randomized parallel trial, 36 healthy participants were assigned to three groups: a control group, a group consuming 10 g/day PUV-treated PC (PC-10 g), and a group consuming 100 g/day PUV-treated PC (PC-100 g). Blood samples collected pre- and post-intervention measured serum 25(OH)D<sub>2</sub>, 25(OH)D<sub>3</sub>, and biochemical parameters. After four weeks, serum 25(OH)D<sub>2</sub> levels significantly increased in the PC-10 g group (1.47 ± 1.42 ng/mL to 9.50 ± 7.10 ng/mL, <i>p</i> = 0.001) and in the PC-100 g group (1.94 ± 2.15 ng/mL to 21.82 ± 16.75 ng/mL, <i>p</i> = 0.002), showing a 10.2-fold rise. The PC-100 g group also experienced a 37.6% reduction in serum intact parathyroid hormone (I-PTH) levels (26.26 ± 9.84 pg/mL to 16.38 ± 5.53 pg/mL). No adverse effects were reported. PUV-treated PC mushrooms significantly increase serum 25(OH)D<sub>2</sub> levels and reduce I-PTH, particularly at higher doses. These findings underscore the potential of vitamin-D-enriched PC as a sustainable, fungi-derived food source for addressing vitamin D deficiency. |
| format | Article |
| id | doaj-art-6b51336f8b43423d990a6bb78cb639bb |
| institution | Kabale University |
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| language | English |
| publishDate | 2025-01-01 |
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| spelling | doaj-art-6b51336f8b43423d990a6bb78cb639bb2025-01-24T13:33:03ZengMDPI AGFoods2304-81582025-01-0114225910.3390/foods14020259Effects of Consuming Pulsed UV Light-Treated <i>Pleurotus citrinopileatus</i> on Vitamin D Nutritional Status in Healthy AdultsChih-Ching Hsu0Chiao-Ming Chen1Yu-Ming Ju2Yu-Ching Wu3Huei-Mei Hsieh4Shu-Hui Yang5Chien-Tien Su6Te-Chao Fang7Widiastuti Setyaningsih8Sing-Chung Li9School of Nutrition and Health Sciences, College of Nutrition, Taipei Medical University, Taipei 11031, TaiwanDepartment of Food Science, Nutrition, and Nutraceutical Biotechnology, Shih Chien University, Taipei 10462, TaiwanInstitute of Plant and Microbial Biology, Academia Sinica, Taipei 11529, TaiwanInstitute of Plant and Microbial Biology, Academia Sinica, Taipei 11529, TaiwanInstitute of Plant and Microbial Biology, Academia Sinica, Taipei 11529, TaiwanTaiwan Agricultural Research Institute, Fengshan Tropical Horticultural Experiment Branch, Kaohsiung City 83052, TaiwanDepartment of Family Medicine, Taipei Medical University Hospital, Taipei 11031, TaiwanDivision of Nephrology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, TaiwanDepartment of Food and Agricultural Product Technology, Faculty of Agricultural Technology, Universitas Gadjah Mada, Jalan Flora, Depok, Sleman, Yogyakarta 55281, IndonesiaSchool of Nutrition and Health Sciences, College of Nutrition, Taipei Medical University, Taipei 11031, TaiwanVitamin D, essential for growth and health, is often deficient in Taiwan despite abundant sunlight. Plant-derived vitamin D<sub>2</sub> (ergocalciferol) is bioavailable, environmentally friendly, and cost-effective. This study evaluated the efficacy of enhancing <i>Pleurotus citrinopileatus</i> (PC) mushrooms’ vitamin D<sub>2</sub> content through pulsed ultraviolet (PUV) light and its impact on vitamin D status in humans. In a four-week randomized parallel trial, 36 healthy participants were assigned to three groups: a control group, a group consuming 10 g/day PUV-treated PC (PC-10 g), and a group consuming 100 g/day PUV-treated PC (PC-100 g). Blood samples collected pre- and post-intervention measured serum 25(OH)D<sub>2</sub>, 25(OH)D<sub>3</sub>, and biochemical parameters. After four weeks, serum 25(OH)D<sub>2</sub> levels significantly increased in the PC-10 g group (1.47 ± 1.42 ng/mL to 9.50 ± 7.10 ng/mL, <i>p</i> = 0.001) and in the PC-100 g group (1.94 ± 2.15 ng/mL to 21.82 ± 16.75 ng/mL, <i>p</i> = 0.002), showing a 10.2-fold rise. The PC-100 g group also experienced a 37.6% reduction in serum intact parathyroid hormone (I-PTH) levels (26.26 ± 9.84 pg/mL to 16.38 ± 5.53 pg/mL). No adverse effects were reported. PUV-treated PC mushrooms significantly increase serum 25(OH)D<sub>2</sub> levels and reduce I-PTH, particularly at higher doses. These findings underscore the potential of vitamin-D-enriched PC as a sustainable, fungi-derived food source for addressing vitamin D deficiency.https://www.mdpi.com/2304-8158/14/2/259vitamin D<sub>2</sub>ergosterol<i>Pleurotus citrinopileatus</i>pulsed ultraviolet light25(OH)D<sub>2</sub>intact parathyroid hormone |
| spellingShingle | Chih-Ching Hsu Chiao-Ming Chen Yu-Ming Ju Yu-Ching Wu Huei-Mei Hsieh Shu-Hui Yang Chien-Tien Su Te-Chao Fang Widiastuti Setyaningsih Sing-Chung Li Effects of Consuming Pulsed UV Light-Treated <i>Pleurotus citrinopileatus</i> on Vitamin D Nutritional Status in Healthy Adults Foods vitamin D<sub>2</sub> ergosterol <i>Pleurotus citrinopileatus</i> pulsed ultraviolet light 25(OH)D<sub>2</sub> intact parathyroid hormone |
| title | Effects of Consuming Pulsed UV Light-Treated <i>Pleurotus citrinopileatus</i> on Vitamin D Nutritional Status in Healthy Adults |
| title_full | Effects of Consuming Pulsed UV Light-Treated <i>Pleurotus citrinopileatus</i> on Vitamin D Nutritional Status in Healthy Adults |
| title_fullStr | Effects of Consuming Pulsed UV Light-Treated <i>Pleurotus citrinopileatus</i> on Vitamin D Nutritional Status in Healthy Adults |
| title_full_unstemmed | Effects of Consuming Pulsed UV Light-Treated <i>Pleurotus citrinopileatus</i> on Vitamin D Nutritional Status in Healthy Adults |
| title_short | Effects of Consuming Pulsed UV Light-Treated <i>Pleurotus citrinopileatus</i> on Vitamin D Nutritional Status in Healthy Adults |
| title_sort | effects of consuming pulsed uv light treated i pleurotus citrinopileatus i on vitamin d nutritional status in healthy adults |
| topic | vitamin D<sub>2</sub> ergosterol <i>Pleurotus citrinopileatus</i> pulsed ultraviolet light 25(OH)D<sub>2</sub> intact parathyroid hormone |
| url | https://www.mdpi.com/2304-8158/14/2/259 |
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