Non-motor Disorders and their Neuro-anatomical Substrate in Parkinson's Disease
Parkinson's disease remains the second most common degenerative disorder of the central nervous system after Alzheimer's. Although it was initially described as a condition with an exclusive motor disorder, it has been shown that non-motor disorders of Parkinson's are an important par...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | Spanish |
| Published: |
Universidad de las Ciencias Médicas de Cienfuegos
2024-12-01
|
| Series: | Revista Finlay |
| Subjects: | |
| Online Access: | https://revfinlay.sld.cu/index.php/finlay/article/view/1466 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832577394459803648 |
|---|---|
| author | Julio López Argüelles Leydi María Sosa Águila |
| author_facet | Julio López Argüelles Leydi María Sosa Águila |
| author_sort | Julio López Argüelles |
| collection | DOAJ |
| description | Parkinson's disease remains the second most common degenerative disorder of the central nervous system after Alzheimer's. Although it was initially described as a condition with an exclusive motor disorder, it has been shown that non-motor disorders of Parkinson's are an important part of the clinical picture. These include all those disorders that are not motor symptoms: behavioral neuropsychiatric disorders (dementia, depression, anxiety, psychosis); autonomic alteration (postural hypotension, gastrointestinal and genitourinary disorders, diaphoresis); sleep disorders; sensory-motor symptoms (fatigue, restless legs syndrome). Degeneration of non-dopaminergic cellular systems (noradrenergic, serotonergic, and cholinergic) is believed to underlie the development of most non-motor disorders. New studies are necessary to clarify the pathophysiological bases of Parkinson's disease that allow establishing future therapeutic strategies for the follow-up of patients with these disorders. |
| format | Article |
| id | doaj-art-6b4c568a8e1d41a991190944cd9f3c9b |
| institution | Kabale University |
| issn | 2221-2434 |
| language | Spanish |
| publishDate | 2024-12-01 |
| publisher | Universidad de las Ciencias Médicas de Cienfuegos |
| record_format | Article |
| series | Revista Finlay |
| spelling | doaj-art-6b4c568a8e1d41a991190944cd9f3c9b2025-01-30T21:22:03ZspaUniversidad de las Ciencias Médicas de CienfuegosRevista Finlay2221-24342024-12-01150e1466e1466747Non-motor Disorders and their Neuro-anatomical Substrate in Parkinson's DiseaseJulio López Argüelles0Leydi María Sosa Águila1Hospital General Universitario Dr. Gustavo Aldereguía Lima. Cienfuegos.Hospital Pediátrico Universitario Paquito González Cueto. Cienfuegos.Parkinson's disease remains the second most common degenerative disorder of the central nervous system after Alzheimer's. Although it was initially described as a condition with an exclusive motor disorder, it has been shown that non-motor disorders of Parkinson's are an important part of the clinical picture. These include all those disorders that are not motor symptoms: behavioral neuropsychiatric disorders (dementia, depression, anxiety, psychosis); autonomic alteration (postural hypotension, gastrointestinal and genitourinary disorders, diaphoresis); sleep disorders; sensory-motor symptoms (fatigue, restless legs syndrome). Degeneration of non-dopaminergic cellular systems (noradrenergic, serotonergic, and cholinergic) is believed to underlie the development of most non-motor disorders. New studies are necessary to clarify the pathophysiological bases of Parkinson's disease that allow establishing future therapeutic strategies for the follow-up of patients with these disorders.https://revfinlay.sld.cu/index.php/finlay/article/view/1466enfermedad de parkinsonsistema nervioso centralestudios clínicos |
| spellingShingle | Julio López Argüelles Leydi María Sosa Águila Non-motor Disorders and their Neuro-anatomical Substrate in Parkinson's Disease Revista Finlay enfermedad de parkinson sistema nervioso central estudios clínicos |
| title | Non-motor Disorders and their Neuro-anatomical Substrate in Parkinson's Disease |
| title_full | Non-motor Disorders and their Neuro-anatomical Substrate in Parkinson's Disease |
| title_fullStr | Non-motor Disorders and their Neuro-anatomical Substrate in Parkinson's Disease |
| title_full_unstemmed | Non-motor Disorders and their Neuro-anatomical Substrate in Parkinson's Disease |
| title_short | Non-motor Disorders and their Neuro-anatomical Substrate in Parkinson's Disease |
| title_sort | non motor disorders and their neuro anatomical substrate in parkinson s disease |
| topic | enfermedad de parkinson sistema nervioso central estudios clínicos |
| url | https://revfinlay.sld.cu/index.php/finlay/article/view/1466 |
| work_keys_str_mv | AT juliolopezarguelles nonmotordisordersandtheirneuroanatomicalsubstrateinparkinsonsdisease AT leydimariasosaaguila nonmotordisordersandtheirneuroanatomicalsubstrateinparkinsonsdisease |