Pharmacotherapeutic Follow-Up and Pharmacovigilance on a Colombian Neurological and Pain Health Service Provider Institution
BACKGROUND: Pharmacotherapy follow-up and pharmacovigilance are activities done exclusively by the community pharmacist, within the framework of pharmaceutical care. The first is patient-oriented and helps in the detection of drug-related negative medication outcomes – NMO (of necessity, effectiven...
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Universidad de Antioquia
2025-06-01
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| Series: | Vitae |
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| Online Access: | https://revistas.udea.edu.co/index.php/vitae/article/view/357710 |
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| author | Milena ORTIZ-RENDÓN Laura CARDONA-ALZATE |
| author_facet | Milena ORTIZ-RENDÓN Laura CARDONA-ALZATE |
| author_sort | Milena ORTIZ-RENDÓN |
| collection | DOAJ |
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BACKGROUND: Pharmacotherapy follow-up and pharmacovigilance are activities done exclusively by the community pharmacist, within the framework of pharmaceutical care. The first is patient-oriented and helps in the detection of drug-related negative medication outcomes – NMO (of necessity, effectiveness, or safety) and drug-related problems – DRP (availability, prescription, dispensing, administration, quality, or use), while the second is oriented to medications and their safety, by systematically evaluating Adverse Drug Reactions – ADRs and their causality. OBJECTIVE: To identify potential NMOs and DRPs associated with the use of medications in ambulatory patients through pharmacotherapeutic follow-up and pharmacovigilance activities. METHODS: Of the total number of patients for whom the medication was authorized, the minimum statistical sample (CI=95%, α=5%) was calculated for each drug, and a literature review was performed to determine the criteria for the evaluation of necessity, effectiveness, and safety. RESULTS: Patients showed good adherence to the evaluated drugs, being the lowest found of 72,4% for acetaminophen/hydrocodone. An incidence of DNO of 24,4% was found, being the nonquantitative lack of safety DNOs the most frequent (17,8%); the incidence of DRP was 22,6%, being the inappropriate use of the medication the most relevant (17,3%). Drug interactions found during the process were intervened with the patient or physician, as necessary. CONCLUSIONS: Pharmacotherapy follow-up and pharmacovigilance are important activities, especially in outpatients, since it allows the identification and early intervention of DNO and DRP to avoid the detriment of the patient's health.
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| format | Article |
| id | doaj-art-6b47e4c38f904d278bf9f95dc0cad75b |
| institution | DOAJ |
| issn | 0121-4004 2145-2660 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Universidad de Antioquia |
| record_format | Article |
| series | Vitae |
| spelling | doaj-art-6b47e4c38f904d278bf9f95dc0cad75b2025-08-20T03:07:39ZengUniversidad de AntioquiaVitae0121-40042145-26602025-06-0132210.17533/udea.vitae.v32n2a357710Pharmacotherapeutic Follow-Up and Pharmacovigilance on a Colombian Neurological and Pain Health Service Provider InstitutionMilena ORTIZ-RENDÓN0Laura CARDONA-ALZATE1Universidad de AntioquiaUniversidad de Antioquia BACKGROUND: Pharmacotherapy follow-up and pharmacovigilance are activities done exclusively by the community pharmacist, within the framework of pharmaceutical care. The first is patient-oriented and helps in the detection of drug-related negative medication outcomes – NMO (of necessity, effectiveness, or safety) and drug-related problems – DRP (availability, prescription, dispensing, administration, quality, or use), while the second is oriented to medications and their safety, by systematically evaluating Adverse Drug Reactions – ADRs and their causality. OBJECTIVE: To identify potential NMOs and DRPs associated with the use of medications in ambulatory patients through pharmacotherapeutic follow-up and pharmacovigilance activities. METHODS: Of the total number of patients for whom the medication was authorized, the minimum statistical sample (CI=95%, α=5%) was calculated for each drug, and a literature review was performed to determine the criteria for the evaluation of necessity, effectiveness, and safety. RESULTS: Patients showed good adherence to the evaluated drugs, being the lowest found of 72,4% for acetaminophen/hydrocodone. An incidence of DNO of 24,4% was found, being the nonquantitative lack of safety DNOs the most frequent (17,8%); the incidence of DRP was 22,6%, being the inappropriate use of the medication the most relevant (17,3%). Drug interactions found during the process were intervened with the patient or physician, as necessary. CONCLUSIONS: Pharmacotherapy follow-up and pharmacovigilance are important activities, especially in outpatients, since it allows the identification and early intervention of DNO and DRP to avoid the detriment of the patient's health. https://revistas.udea.edu.co/index.php/vitae/article/view/357710Pharmacotherapy follow-uppharmacovigilancepharmaceutical carepharmacist interventionpharmacist |
| spellingShingle | Milena ORTIZ-RENDÓN Laura CARDONA-ALZATE Pharmacotherapeutic Follow-Up and Pharmacovigilance on a Colombian Neurological and Pain Health Service Provider Institution Vitae Pharmacotherapy follow-up pharmacovigilance pharmaceutical care pharmacist intervention pharmacist |
| title | Pharmacotherapeutic Follow-Up and Pharmacovigilance on a Colombian Neurological and Pain Health Service Provider Institution |
| title_full | Pharmacotherapeutic Follow-Up and Pharmacovigilance on a Colombian Neurological and Pain Health Service Provider Institution |
| title_fullStr | Pharmacotherapeutic Follow-Up and Pharmacovigilance on a Colombian Neurological and Pain Health Service Provider Institution |
| title_full_unstemmed | Pharmacotherapeutic Follow-Up and Pharmacovigilance on a Colombian Neurological and Pain Health Service Provider Institution |
| title_short | Pharmacotherapeutic Follow-Up and Pharmacovigilance on a Colombian Neurological and Pain Health Service Provider Institution |
| title_sort | pharmacotherapeutic follow up and pharmacovigilance on a colombian neurological and pain health service provider institution |
| topic | Pharmacotherapy follow-up pharmacovigilance pharmaceutical care pharmacist intervention pharmacist |
| url | https://revistas.udea.edu.co/index.php/vitae/article/view/357710 |
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