Outcomes of holmium laser enucleation of the prostate in men with a history of prostatitis: a retrospective study

Background: Prostatitis can be challenging to treat. In refractory cases, prostatitis can be treated surgically with transurethral resection. Objectives: To examine the safety and efficacy of holmium laser enucleation of the prostate (HoLEP) as treatment in patients with prostatitis. Design and meth...

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Main Authors: Meera Bhanu Ganesh, Perry Xu, Nicholas Dean, Kyle Tsai, Jamie Michael, Alyssa McDonald, Devyn Taylor Coskey, Nabila Khondakar, Allaa Fadl-Alla, Amy Elizabeth Krambeck
Format: Article
Language:English
Published: SAGE Publishing 2025-05-01
Series:Therapeutic Advances in Urology
Online Access:https://doi.org/10.1177/17562872251338430
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author Meera Bhanu Ganesh
Perry Xu
Nicholas Dean
Kyle Tsai
Jamie Michael
Alyssa McDonald
Devyn Taylor Coskey
Nabila Khondakar
Allaa Fadl-Alla
Amy Elizabeth Krambeck
author_facet Meera Bhanu Ganesh
Perry Xu
Nicholas Dean
Kyle Tsai
Jamie Michael
Alyssa McDonald
Devyn Taylor Coskey
Nabila Khondakar
Allaa Fadl-Alla
Amy Elizabeth Krambeck
author_sort Meera Bhanu Ganesh
collection DOAJ
description Background: Prostatitis can be challenging to treat. In refractory cases, prostatitis can be treated surgically with transurethral resection. Objectives: To examine the safety and efficacy of holmium laser enucleation of the prostate (HoLEP) as treatment in patients with prostatitis. Design and methods: Patients who underwent HoLEP at a single center between January 2021 and August 2023 were retrospectively reviewed. Preoperative, intraoperative, and postoperative parameters were collected and analyzed. Patients with an ICD-10 diagnosis of prostatitis were identified and contacted postoperatively to evaluate for recurrent symptoms. Statistical significance was defined as p  < 0.05. Results: We identified 918 patients, of whom 26 (2.8%) had a diagnosis of prostatitis. There were no differences in baseline characteristics between patients with and without prostatitis. Patients with prostatitis were less likely to have a history of a neurologic disorder ( p  = 0.035), less likely to be catheter-dependent ( p  = 0.005), and less likely to have a preoperative positive urine culture ( p  = 0.040). There were no significant differences in intraoperative and postoperative parameters between the two groups. There were 23/26 (88.5%) patients with follow-up. There were no episodes of recurrent prostatitis and one episode of UTI after surgery, with a mean follow-up of 19.39 months (range: 7.45–30.19, SD: 7.38). Conclusion: Prostatitis patients undergoing HoLEP had comparable safety and efficacy profiles to those who did not have prostatitis. On follow-up, 100% of patients with prostatitis did not experience recurrent prostatitis, suggesting that HoLEP may have a role in the management of prostatitis in the presence of benign prostatic enlargement.
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spelling doaj-art-6b3e5c814d6d4d3a82f1243f08d87b292025-08-20T03:10:25ZengSAGE PublishingTherapeutic Advances in Urology1756-28802025-05-011710.1177/17562872251338430Outcomes of holmium laser enucleation of the prostate in men with a history of prostatitis: a retrospective studyMeera Bhanu GaneshPerry XuNicholas DeanKyle TsaiJamie MichaelAlyssa McDonaldDevyn Taylor CoskeyNabila KhondakarAllaa Fadl-AllaAmy Elizabeth KrambeckBackground: Prostatitis can be challenging to treat. In refractory cases, prostatitis can be treated surgically with transurethral resection. Objectives: To examine the safety and efficacy of holmium laser enucleation of the prostate (HoLEP) as treatment in patients with prostatitis. Design and methods: Patients who underwent HoLEP at a single center between January 2021 and August 2023 were retrospectively reviewed. Preoperative, intraoperative, and postoperative parameters were collected and analyzed. Patients with an ICD-10 diagnosis of prostatitis were identified and contacted postoperatively to evaluate for recurrent symptoms. Statistical significance was defined as p  < 0.05. Results: We identified 918 patients, of whom 26 (2.8%) had a diagnosis of prostatitis. There were no differences in baseline characteristics between patients with and without prostatitis. Patients with prostatitis were less likely to have a history of a neurologic disorder ( p  = 0.035), less likely to be catheter-dependent ( p  = 0.005), and less likely to have a preoperative positive urine culture ( p  = 0.040). There were no significant differences in intraoperative and postoperative parameters between the two groups. There were 23/26 (88.5%) patients with follow-up. There were no episodes of recurrent prostatitis and one episode of UTI after surgery, with a mean follow-up of 19.39 months (range: 7.45–30.19, SD: 7.38). Conclusion: Prostatitis patients undergoing HoLEP had comparable safety and efficacy profiles to those who did not have prostatitis. On follow-up, 100% of patients with prostatitis did not experience recurrent prostatitis, suggesting that HoLEP may have a role in the management of prostatitis in the presence of benign prostatic enlargement.https://doi.org/10.1177/17562872251338430
spellingShingle Meera Bhanu Ganesh
Perry Xu
Nicholas Dean
Kyle Tsai
Jamie Michael
Alyssa McDonald
Devyn Taylor Coskey
Nabila Khondakar
Allaa Fadl-Alla
Amy Elizabeth Krambeck
Outcomes of holmium laser enucleation of the prostate in men with a history of prostatitis: a retrospective study
Therapeutic Advances in Urology
title Outcomes of holmium laser enucleation of the prostate in men with a history of prostatitis: a retrospective study
title_full Outcomes of holmium laser enucleation of the prostate in men with a history of prostatitis: a retrospective study
title_fullStr Outcomes of holmium laser enucleation of the prostate in men with a history of prostatitis: a retrospective study
title_full_unstemmed Outcomes of holmium laser enucleation of the prostate in men with a history of prostatitis: a retrospective study
title_short Outcomes of holmium laser enucleation of the prostate in men with a history of prostatitis: a retrospective study
title_sort outcomes of holmium laser enucleation of the prostate in men with a history of prostatitis a retrospective study
url https://doi.org/10.1177/17562872251338430
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