Nano-ZnO Catalyzed Green and Efficient One-Pot Four-Component Synthesis of Pyranopyrazoles
An efficient zinc oxide nanoparticle catalyzed one-pot, four-component synthesis of 6-amino-3-methyl-5-cyano-4-aryl-1,4-dihydropyrano[2,3-c]pyrazoles from aromatic aldehyde, malononitrile, ethyl acetoacetate, and hydrazine hydrate in aqueous medium is described. Since water was employed as the react...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2013/840954 |
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| author | Sunil U. Tekale Sushma S. Kauthale Kavita M. Jadhav Rajendra P. Pawar |
| author_facet | Sunil U. Tekale Sushma S. Kauthale Kavita M. Jadhav Rajendra P. Pawar |
| author_sort | Sunil U. Tekale |
| collection | DOAJ |
| description | An efficient zinc oxide nanoparticle catalyzed one-pot, four-component synthesis of 6-amino-3-methyl-5-cyano-4-aryl-1,4-dihydropyrano[2,3-c]pyrazoles from aromatic aldehyde, malononitrile, ethyl acetoacetate, and hydrazine hydrate in aqueous medium is described. Since water was employed as the reaction medium, it serves as a green route for the synthesis of pyrano[2,3-c]pyrazoles. The advantages associated with the present protocol include nonchromatographic purification technique, use of recyclable heterogeneous nano-ZnO catalyst in aqueous medium, and short reaction time. It combines successfully the synergistic effect of green chemistry with nanocatalysis. |
| format | Article |
| id | doaj-art-6b079182875b4aef912f7416a60661e0 |
| institution | Kabale University |
| issn | 2090-9063 2090-9071 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Chemistry |
| spelling | doaj-art-6b079182875b4aef912f7416a60661e02025-02-03T06:11:12ZengWileyJournal of Chemistry2090-90632090-90712013-01-01201310.1155/2013/840954840954Nano-ZnO Catalyzed Green and Efficient One-Pot Four-Component Synthesis of PyranopyrazolesSunil U. Tekale0Sushma S. Kauthale1Kavita M. Jadhav2Rajendra P. Pawar3Department of Chemistry, Shri Muktanand College, Gangapur, Maharashtra 431 109, IndiaDepartment of Chemistry, Deogiri College, Station Road, Aurangabad, Maharashtra 431 005, IndiaDepartment of Chemistry, Deogiri College, Station Road, Aurangabad, Maharashtra 431 005, IndiaDepartment of Chemistry, Deogiri College, Station Road, Aurangabad, Maharashtra 431 005, IndiaAn efficient zinc oxide nanoparticle catalyzed one-pot, four-component synthesis of 6-amino-3-methyl-5-cyano-4-aryl-1,4-dihydropyrano[2,3-c]pyrazoles from aromatic aldehyde, malononitrile, ethyl acetoacetate, and hydrazine hydrate in aqueous medium is described. Since water was employed as the reaction medium, it serves as a green route for the synthesis of pyrano[2,3-c]pyrazoles. The advantages associated with the present protocol include nonchromatographic purification technique, use of recyclable heterogeneous nano-ZnO catalyst in aqueous medium, and short reaction time. It combines successfully the synergistic effect of green chemistry with nanocatalysis.http://dx.doi.org/10.1155/2013/840954 |
| spellingShingle | Sunil U. Tekale Sushma S. Kauthale Kavita M. Jadhav Rajendra P. Pawar Nano-ZnO Catalyzed Green and Efficient One-Pot Four-Component Synthesis of Pyranopyrazoles Journal of Chemistry |
| title | Nano-ZnO Catalyzed Green and Efficient One-Pot Four-Component Synthesis of Pyranopyrazoles |
| title_full | Nano-ZnO Catalyzed Green and Efficient One-Pot Four-Component Synthesis of Pyranopyrazoles |
| title_fullStr | Nano-ZnO Catalyzed Green and Efficient One-Pot Four-Component Synthesis of Pyranopyrazoles |
| title_full_unstemmed | Nano-ZnO Catalyzed Green and Efficient One-Pot Four-Component Synthesis of Pyranopyrazoles |
| title_short | Nano-ZnO Catalyzed Green and Efficient One-Pot Four-Component Synthesis of Pyranopyrazoles |
| title_sort | nano zno catalyzed green and efficient one pot four component synthesis of pyranopyrazoles |
| url | http://dx.doi.org/10.1155/2013/840954 |
| work_keys_str_mv | AT sunilutekale nanoznocatalyzedgreenandefficientonepotfourcomponentsynthesisofpyranopyrazoles AT sushmaskauthale nanoznocatalyzedgreenandefficientonepotfourcomponentsynthesisofpyranopyrazoles AT kavitamjadhav nanoznocatalyzedgreenandefficientonepotfourcomponentsynthesisofpyranopyrazoles AT rajendrappawar nanoznocatalyzedgreenandefficientonepotfourcomponentsynthesisofpyranopyrazoles |