FOLFOX Induced Takotsubo Cardiomyopathy Treated with Impella Assist Device

Chemotherapy induced cardiotoxicity is becoming increasingly prevalent with several new agents being used recently. The incidence of Takotsubo cardiomyopathy due to 5-fluorouracil based chemotherapeutic regimens like FOLFOX is not uncommon. It is also seen with platinum based chemotherapy. Most of t...

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Main Authors: Swethika Sundaravel, Abdulah Alrifai, Mohamad Kabach, Waqas Ghumman
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Cardiology
Online Access:http://dx.doi.org/10.1155/2017/8507096
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author Swethika Sundaravel
Abdulah Alrifai
Mohamad Kabach
Waqas Ghumman
author_facet Swethika Sundaravel
Abdulah Alrifai
Mohamad Kabach
Waqas Ghumman
author_sort Swethika Sundaravel
collection DOAJ
description Chemotherapy induced cardiotoxicity is becoming increasingly prevalent with several new agents being used recently. The incidence of Takotsubo cardiomyopathy due to 5-fluorouracil based chemotherapeutic regimens like FOLFOX is not uncommon. It is also seen with platinum based chemotherapy. Most of these patients have reversible cardiotoxicity and the cardiac function recovers within a short period with supportive treatment. Here we have a patient who presented with cardiogenic shock after 5 days of receiving FOLFOX regimen for colorectal adenocarcinoma. She was treated with a percutaneous left ventricular assist device, Impella CP, for hemodynamic support with excellent outcome.
format Article
id doaj-art-6ae7240b1b3743e0800497b903c4fd84
institution Kabale University
issn 2090-6404
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language English
publishDate 2017-01-01
publisher Wiley
record_format Article
series Case Reports in Cardiology
spelling doaj-art-6ae7240b1b3743e0800497b903c4fd842025-02-03T05:47:57ZengWileyCase Reports in Cardiology2090-64042090-64122017-01-01201710.1155/2017/85070968507096FOLFOX Induced Takotsubo Cardiomyopathy Treated with Impella Assist DeviceSwethika Sundaravel0Abdulah Alrifai1Mohamad Kabach2Waqas Ghumman3Internal Medicine, University of Miami, Palm Beach Regional Consortium, Atlantis, FL, USACardiology, University of Miami, Palm Beach Regional Consortium, Atlantis, FL, USACardiology, University of Miami, Palm Beach Regional Consortium, Atlantis, FL, USACardiology, University of Miami, Palm Beach Regional Consortium, Atlantis, FL, USAChemotherapy induced cardiotoxicity is becoming increasingly prevalent with several new agents being used recently. The incidence of Takotsubo cardiomyopathy due to 5-fluorouracil based chemotherapeutic regimens like FOLFOX is not uncommon. It is also seen with platinum based chemotherapy. Most of these patients have reversible cardiotoxicity and the cardiac function recovers within a short period with supportive treatment. Here we have a patient who presented with cardiogenic shock after 5 days of receiving FOLFOX regimen for colorectal adenocarcinoma. She was treated with a percutaneous left ventricular assist device, Impella CP, for hemodynamic support with excellent outcome.http://dx.doi.org/10.1155/2017/8507096
spellingShingle Swethika Sundaravel
Abdulah Alrifai
Mohamad Kabach
Waqas Ghumman
FOLFOX Induced Takotsubo Cardiomyopathy Treated with Impella Assist Device
Case Reports in Cardiology
title FOLFOX Induced Takotsubo Cardiomyopathy Treated with Impella Assist Device
title_full FOLFOX Induced Takotsubo Cardiomyopathy Treated with Impella Assist Device
title_fullStr FOLFOX Induced Takotsubo Cardiomyopathy Treated with Impella Assist Device
title_full_unstemmed FOLFOX Induced Takotsubo Cardiomyopathy Treated with Impella Assist Device
title_short FOLFOX Induced Takotsubo Cardiomyopathy Treated with Impella Assist Device
title_sort folfox induced takotsubo cardiomyopathy treated with impella assist device
url http://dx.doi.org/10.1155/2017/8507096
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AT abdulahalrifai folfoxinducedtakotsubocardiomyopathytreatedwithimpellaassistdevice
AT mohamadkabach folfoxinducedtakotsubocardiomyopathytreatedwithimpellaassistdevice
AT waqasghumman folfoxinducedtakotsubocardiomyopathytreatedwithimpellaassistdevice