The Role of Human Gut Microbe Ruminococcus gnavus in Inflammatory Diseases
Dysbiosis is a prominent factor in numerous inflammatory conditions, with Ruminococcus gnavus, a prevalent gut microbe, implicated in inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), eczema, metabolic disorders, and rheumatic diseases. R. gnavus contributes to inflammation by produ...
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| Format: | Article |
| Language: | English |
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HH Publisher
2023-12-01
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| Series: | Progress in Microbes and Molecular Biology |
| Online Access: | https://journals.hh-publisher.com/index.php/pmmb/article/view/924 |
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| author | Sasmitra Kandasamy Vengadesh Letchumanan Kar Wai Hong Kah-Ooi Chua Nurul Syakima Ab Mutalib Alvin Lai Oon Ng Long Chiau Ming Hui Xuan Lim Sivakumar Thurairajasingam Jodi Woan-Fei Law Loh Teng-Hern Tan |
| author_facet | Sasmitra Kandasamy Vengadesh Letchumanan Kar Wai Hong Kah-Ooi Chua Nurul Syakima Ab Mutalib Alvin Lai Oon Ng Long Chiau Ming Hui Xuan Lim Sivakumar Thurairajasingam Jodi Woan-Fei Law Loh Teng-Hern Tan |
| author_sort | Sasmitra Kandasamy |
| collection | DOAJ |
| description |
Dysbiosis is a prominent factor in numerous inflammatory conditions, with Ruminococcus gnavus, a prevalent gut microbe, implicated in inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), eczema, metabolic disorders, and rheumatic diseases. R. gnavus contributes to inflammation by producing an inflammatory polysaccharide and degrading mucin. The increasing evidence of elevated R. gnavus abundance in various inflammatory conditions suggests its potential as a therapeutic target. Despite this, there are limited studies on treatment strategies targeting R. gnavus. This article provides a comprehensive overview of the association between R. gnavus and diverse inflammatory conditions, highlighting the need for further research to explore effective treatment options against this bacterium.
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| format | Article |
| id | doaj-art-6abdb2dc966b4fceabf950e4bf2f1786 |
| institution | Kabale University |
| issn | 2637-1049 |
| language | English |
| publishDate | 2023-12-01 |
| publisher | HH Publisher |
| record_format | Article |
| series | Progress in Microbes and Molecular Biology |
| spelling | doaj-art-6abdb2dc966b4fceabf950e4bf2f17862025-02-04T08:39:42ZengHH PublisherProgress in Microbes and Molecular Biology2637-10492023-12-016110.36877/pmmb.a0000396The Role of Human Gut Microbe Ruminococcus gnavus in Inflammatory DiseasesSasmitra KandasamyVengadesh LetchumananKar Wai HongKah-Ooi ChuaNurul Syakima Ab MutalibAlvin Lai Oon NgLong Chiau MingHui Xuan LimSivakumar ThurairajasingamJodi Woan-Fei LawLoh Teng-Hern Tan Dysbiosis is a prominent factor in numerous inflammatory conditions, with Ruminococcus gnavus, a prevalent gut microbe, implicated in inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), eczema, metabolic disorders, and rheumatic diseases. R. gnavus contributes to inflammation by producing an inflammatory polysaccharide and degrading mucin. The increasing evidence of elevated R. gnavus abundance in various inflammatory conditions suggests its potential as a therapeutic target. Despite this, there are limited studies on treatment strategies targeting R. gnavus. This article provides a comprehensive overview of the association between R. gnavus and diverse inflammatory conditions, highlighting the need for further research to explore effective treatment options against this bacterium. https://journals.hh-publisher.com/index.php/pmmb/article/view/924 |
| spellingShingle | Sasmitra Kandasamy Vengadesh Letchumanan Kar Wai Hong Kah-Ooi Chua Nurul Syakima Ab Mutalib Alvin Lai Oon Ng Long Chiau Ming Hui Xuan Lim Sivakumar Thurairajasingam Jodi Woan-Fei Law Loh Teng-Hern Tan The Role of Human Gut Microbe Ruminococcus gnavus in Inflammatory Diseases Progress in Microbes and Molecular Biology |
| title | The Role of Human Gut Microbe Ruminococcus gnavus in Inflammatory Diseases |
| title_full | The Role of Human Gut Microbe Ruminococcus gnavus in Inflammatory Diseases |
| title_fullStr | The Role of Human Gut Microbe Ruminococcus gnavus in Inflammatory Diseases |
| title_full_unstemmed | The Role of Human Gut Microbe Ruminococcus gnavus in Inflammatory Diseases |
| title_short | The Role of Human Gut Microbe Ruminococcus gnavus in Inflammatory Diseases |
| title_sort | role of human gut microbe ruminococcus gnavus in inflammatory diseases |
| url | https://journals.hh-publisher.com/index.php/pmmb/article/view/924 |
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