Cyclodextrin-assisted fluorescein decoration of gold nanoclusters for ratiometric and selective Hg2+ analysis
IntroductionThe construction of nanomaterial-based ratiometric detection systems usually requires covalent modification, which undergoes reactive environments and may change the natural properties of supporting nanomaterials.MethodsIn this study, dualemissive and fluorescein-decorated gold nanoclust...
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Analytical Science |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/frans.2024.1506786/full |
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| author | Siyuan Sun Zhiqin Yuan |
| author_facet | Siyuan Sun Zhiqin Yuan |
| author_sort | Siyuan Sun |
| collection | DOAJ |
| description | IntroductionThe construction of nanomaterial-based ratiometric detection systems usually requires covalent modification, which undergoes reactive environments and may change the natural properties of supporting nanomaterials.MethodsIn this study, dualemissive and fluorescein-decorated gold nanoclusters (F-Au NCs) through cyclodextrin-supported host–guest interaction (non-covalent modification) are explored as ratiometric Hg2+ nanoprobes through d10–d10-interactioncaused fluorescence quenching of Au NCs.Results and DiscussionThe fluorescein decoration only provides a fluorescent internal reference but does not change the Hg2+-Au NCs affinity nature. Ratiometric and selective Hg2+ detection is achieved through the proposed F-Au NC probes with a limit of detection of 15 nM. The Hg2+ analysis in river water samples with small relative standard deviations validates the practical application of these probes. |
| format | Article |
| id | doaj-art-6a92bf4fbe3b43e68160c1c7c1f0e0c0 |
| institution | Kabale University |
| issn | 2673-9283 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Analytical Science |
| spelling | doaj-art-6a92bf4fbe3b43e68160c1c7c1f0e0c02025-01-22T05:19:44ZengFrontiers Media S.A.Frontiers in Analytical Science2673-92832025-01-01410.3389/frans.2024.15067861506786Cyclodextrin-assisted fluorescein decoration of gold nanoclusters for ratiometric and selective Hg2+ analysisSiyuan SunZhiqin YuanIntroductionThe construction of nanomaterial-based ratiometric detection systems usually requires covalent modification, which undergoes reactive environments and may change the natural properties of supporting nanomaterials.MethodsIn this study, dualemissive and fluorescein-decorated gold nanoclusters (F-Au NCs) through cyclodextrin-supported host–guest interaction (non-covalent modification) are explored as ratiometric Hg2+ nanoprobes through d10–d10-interactioncaused fluorescence quenching of Au NCs.Results and DiscussionThe fluorescein decoration only provides a fluorescent internal reference but does not change the Hg2+-Au NCs affinity nature. Ratiometric and selective Hg2+ detection is achieved through the proposed F-Au NC probes with a limit of detection of 15 nM. The Hg2+ analysis in river water samples with small relative standard deviations validates the practical application of these probes.https://www.frontiersin.org/articles/10.3389/frans.2024.1506786/fullratiometric fluorescencegold nanoclustersHg2+ detectiond10-d10 interactionhost–guest interaction |
| spellingShingle | Siyuan Sun Zhiqin Yuan Cyclodextrin-assisted fluorescein decoration of gold nanoclusters for ratiometric and selective Hg2+ analysis Frontiers in Analytical Science ratiometric fluorescence gold nanoclusters Hg2+ detection d10-d10 interaction host–guest interaction |
| title | Cyclodextrin-assisted fluorescein decoration of gold nanoclusters for ratiometric and selective Hg2+ analysis |
| title_full | Cyclodextrin-assisted fluorescein decoration of gold nanoclusters for ratiometric and selective Hg2+ analysis |
| title_fullStr | Cyclodextrin-assisted fluorescein decoration of gold nanoclusters for ratiometric and selective Hg2+ analysis |
| title_full_unstemmed | Cyclodextrin-assisted fluorescein decoration of gold nanoclusters for ratiometric and selective Hg2+ analysis |
| title_short | Cyclodextrin-assisted fluorescein decoration of gold nanoclusters for ratiometric and selective Hg2+ analysis |
| title_sort | cyclodextrin assisted fluorescein decoration of gold nanoclusters for ratiometric and selective hg2 analysis |
| topic | ratiometric fluorescence gold nanoclusters Hg2+ detection d10-d10 interaction host–guest interaction |
| url | https://www.frontiersin.org/articles/10.3389/frans.2024.1506786/full |
| work_keys_str_mv | AT siyuansun cyclodextrinassistedfluoresceindecorationofgoldnanoclustersforratiometricandselectivehg2analysis AT zhiqinyuan cyclodextrinassistedfluoresceindecorationofgoldnanoclustersforratiometricandselectivehg2analysis |