Successful Low-Dose tPA for Mechanical Mitral Valve Thrombosis in a Patient with Postinfarction Contained Left Ventricular Free Wall Rupture
Prosthetic valve thrombosis is a potentially life-threatening complication diagnosed by a combination of clinical features and imaging modalities, but the optimal management in high bleeding risk patients remains controversial. Current treatment options for prosthetic valve thrombosis included surge...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Cardiology |
| Online Access: | http://dx.doi.org/10.1155/2021/5532728 |
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| author | James Livesay Emmanuel Isang Hassan Tahir Raj Baljepally |
| author_facet | James Livesay Emmanuel Isang Hassan Tahir Raj Baljepally |
| author_sort | James Livesay |
| collection | DOAJ |
| description | Prosthetic valve thrombosis is a potentially life-threatening complication diagnosed by a combination of clinical features and imaging modalities, but the optimal management in high bleeding risk patients remains controversial. Current treatment options for prosthetic valve thrombosis included surgery, thrombolytic therapy, and anticoagulation. We present a very unusual case of a patient with a recent ST-elevation myocardial infarction complicated by contained left ventricle free wall rupture and mechanical mitral valve thrombosis. Deemed a high surgical risk candidate, low-dose tissue plasminogen activator was used despite significant bleeding risk from contained left ventricle free wall rupture, which resulted in resolution of the thrombus. To the best of our knowledge, this is the first report of successful thrombolytic therapy for prosthetic mechanical mitral valve thrombosis in a patient with recent postmyocardial infarction contained left ventricular free wall rupture. |
| format | Article |
| id | doaj-art-6a7dceabb1d74c8ba0450ac907786dc9 |
| institution | Kabale University |
| issn | 2090-6404 2090-6412 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Cardiology |
| spelling | doaj-art-6a7dceabb1d74c8ba0450ac907786dc92025-02-03T01:26:58ZengWileyCase Reports in Cardiology2090-64042090-64122021-01-01202110.1155/2021/55327285532728Successful Low-Dose tPA for Mechanical Mitral Valve Thrombosis in a Patient with Postinfarction Contained Left Ventricular Free Wall RuptureJames Livesay0Emmanuel Isang1Hassan Tahir2Raj Baljepally3Department of Medicine, University of Tennessee Graduate School of Medicine, Knoxville, TN, USADepartment of Medicine, University of Tennessee Graduate School of Medicine, Knoxville, TN, USADepartment of Medicine, University of Tennessee Graduate School of Medicine, Knoxville, TN, USADepartment of Medicine, University of Tennessee Graduate School of Medicine, Knoxville, TN, USAProsthetic valve thrombosis is a potentially life-threatening complication diagnosed by a combination of clinical features and imaging modalities, but the optimal management in high bleeding risk patients remains controversial. Current treatment options for prosthetic valve thrombosis included surgery, thrombolytic therapy, and anticoagulation. We present a very unusual case of a patient with a recent ST-elevation myocardial infarction complicated by contained left ventricle free wall rupture and mechanical mitral valve thrombosis. Deemed a high surgical risk candidate, low-dose tissue plasminogen activator was used despite significant bleeding risk from contained left ventricle free wall rupture, which resulted in resolution of the thrombus. To the best of our knowledge, this is the first report of successful thrombolytic therapy for prosthetic mechanical mitral valve thrombosis in a patient with recent postmyocardial infarction contained left ventricular free wall rupture.http://dx.doi.org/10.1155/2021/5532728 |
| spellingShingle | James Livesay Emmanuel Isang Hassan Tahir Raj Baljepally Successful Low-Dose tPA for Mechanical Mitral Valve Thrombosis in a Patient with Postinfarction Contained Left Ventricular Free Wall Rupture Case Reports in Cardiology |
| title | Successful Low-Dose tPA for Mechanical Mitral Valve Thrombosis in a Patient with Postinfarction Contained Left Ventricular Free Wall Rupture |
| title_full | Successful Low-Dose tPA for Mechanical Mitral Valve Thrombosis in a Patient with Postinfarction Contained Left Ventricular Free Wall Rupture |
| title_fullStr | Successful Low-Dose tPA for Mechanical Mitral Valve Thrombosis in a Patient with Postinfarction Contained Left Ventricular Free Wall Rupture |
| title_full_unstemmed | Successful Low-Dose tPA for Mechanical Mitral Valve Thrombosis in a Patient with Postinfarction Contained Left Ventricular Free Wall Rupture |
| title_short | Successful Low-Dose tPA for Mechanical Mitral Valve Thrombosis in a Patient with Postinfarction Contained Left Ventricular Free Wall Rupture |
| title_sort | successful low dose tpa for mechanical mitral valve thrombosis in a patient with postinfarction contained left ventricular free wall rupture |
| url | http://dx.doi.org/10.1155/2021/5532728 |
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