EBV Infection Unmasking a Choledochal Cyst in an Infant
Hepatic involvement is common in acute Epstein–Barr virus (EBV) infection in children. It usually manifests as a transitory elevation of transaminases in up to 80% to 90% of patients, and they normalize by 2 to 6 weeks. A cholestatic pattern with elevated gamma-glutamyl transferase (γGT) and alkalin...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2019/7320109 |
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| _version_ | 1832559489373437952 |
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| author | Hassan El Khatib Batoul Kawtharany Diyaa Mohammad Mohammad Siblini Nahida El-Rifai |
| author_facet | Hassan El Khatib Batoul Kawtharany Diyaa Mohammad Mohammad Siblini Nahida El-Rifai |
| author_sort | Hassan El Khatib |
| collection | DOAJ |
| description | Hepatic involvement is common in acute Epstein–Barr virus (EBV) infection in children. It usually manifests as a transitory elevation of transaminases in up to 80% to 90% of patients, and they normalize by 2 to 6 weeks. A cholestatic pattern with elevated gamma-glutamyl transferase (γGT) and alkaline phosphatase (ALP) is common, in up to 60% in young adults. However, jaundice is very rare occurring in only 5% of pediatric patients. We report here an 8-month-old female with EBV infection who developed obstructive jaundice 2 weeks after the initial infection. Radiologic investigations were compatible with choledochal cyst type IVa complicated by stone formation in the common bile duct. In case of clinical exacerbation or nonamelioration of liver function tests in EVB infection, another diagnosis should be addressed. This highlights the importance of close follow-up in these patients in order not to miss a serious underlying condition such as choledochal malformation. |
| format | Article |
| id | doaj-art-6a6f0d1423634451ac83e93c7680f872 |
| institution | Kabale University |
| issn | 2090-6803 2090-6811 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pediatrics |
| spelling | doaj-art-6a6f0d1423634451ac83e93c7680f8722025-02-03T01:29:54ZengWileyCase Reports in Pediatrics2090-68032090-68112019-01-01201910.1155/2019/73201097320109EBV Infection Unmasking a Choledochal Cyst in an InfantHassan El Khatib0Batoul Kawtharany1Diyaa Mohammad2Mohammad Siblini3Nahida El-Rifai4Department of Pediatrics, Makassed General Hospital, Beirut, LebanonDepartment of Pediatrics, Makassed General Hospital, Beirut, LebanonDepartment of Surgery, Makassed General Hospital, Beirut, LebanonDepartment of Surgery, Makassed General Hospital, Beirut, LebanonDepartment of Pediatrics, Makassed General Hospital, Beirut, LebanonHepatic involvement is common in acute Epstein–Barr virus (EBV) infection in children. It usually manifests as a transitory elevation of transaminases in up to 80% to 90% of patients, and they normalize by 2 to 6 weeks. A cholestatic pattern with elevated gamma-glutamyl transferase (γGT) and alkaline phosphatase (ALP) is common, in up to 60% in young adults. However, jaundice is very rare occurring in only 5% of pediatric patients. We report here an 8-month-old female with EBV infection who developed obstructive jaundice 2 weeks after the initial infection. Radiologic investigations were compatible with choledochal cyst type IVa complicated by stone formation in the common bile duct. In case of clinical exacerbation or nonamelioration of liver function tests in EVB infection, another diagnosis should be addressed. This highlights the importance of close follow-up in these patients in order not to miss a serious underlying condition such as choledochal malformation.http://dx.doi.org/10.1155/2019/7320109 |
| spellingShingle | Hassan El Khatib Batoul Kawtharany Diyaa Mohammad Mohammad Siblini Nahida El-Rifai EBV Infection Unmasking a Choledochal Cyst in an Infant Case Reports in Pediatrics |
| title | EBV Infection Unmasking a Choledochal Cyst in an Infant |
| title_full | EBV Infection Unmasking a Choledochal Cyst in an Infant |
| title_fullStr | EBV Infection Unmasking a Choledochal Cyst in an Infant |
| title_full_unstemmed | EBV Infection Unmasking a Choledochal Cyst in an Infant |
| title_short | EBV Infection Unmasking a Choledochal Cyst in an Infant |
| title_sort | ebv infection unmasking a choledochal cyst in an infant |
| url | http://dx.doi.org/10.1155/2019/7320109 |
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