Indications and Current Surgical Techniques for Keratoplasty: A 10-year Review from 2011 through 2020 at a Tertiary Referral Hospital in Thailand

Objective: To report the indications and current trends in surgical techniques for keratoplasty over 10 years at Siriraj Hospital. Materials and Methods: We retrospectively reviewed the medical records of hospitalized patients who underwent keratoplasty from 2011 to 2020. The collected data compr...

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Main Authors: Wipawee Booranapong, Chayanit Junsangsri, Chareenun Chirapapaisan, Panotsom Ngowyutagon, Sathiya Kengpunpanich
Format: Article
Language:English
Published: Faculty of Medicine Siriraj Hospital 2025-02-01
Series:Siriraj Medical Journal
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Online Access:https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/268932
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author Wipawee Booranapong
Chayanit Junsangsri
Chareenun Chirapapaisan
Panotsom Ngowyutagon
Sathiya Kengpunpanich
author_facet Wipawee Booranapong
Chayanit Junsangsri
Chareenun Chirapapaisan
Panotsom Ngowyutagon
Sathiya Kengpunpanich
author_sort Wipawee Booranapong
collection DOAJ
description Objective: To report the indications and current trends in surgical techniques for keratoplasty over 10 years at Siriraj Hospital. Materials and Methods: We retrospectively reviewed the medical records of hospitalized patients who underwent keratoplasty from 2011 to 2020. The collected data comprised demographics, indications for keratoplasty, and surgical techniques used. Results: A total of 754 eyes were included. Active infectious keratitis was the most common indication (26.1%), followed by bullous keratopathy (20.8%) and regraft (19.2%). There was no significant change in indications for keratoplasty between the first 5-year period and the second 5-year period. Fungal keratitis remained the most common etiology for keratoplasty. Penetrating keratoplasty (PKP) was the most common procedure overall (90.7%), followed by endothelial keratoplasty (EK; 5.7%) and deep anterior lamellar keratoplasty (DALK; 3.6%). However, surgical techniques used in the second 5-year period differed significantly from those in the first 5-year period (P < 0.05). The use of PKP decreased from 96.0% to 86.7%; however, EK increased from 1.5% to 8.9%, while DALK rose slightly from 2.5% to 4.4%. Conclusion: Active infectious keratitis was the most common indication for keratoplasty, followed by bullous keratopathy and regraft. These indications may be reduced through collaborative efforts among government leaders, public health officers, and ophthalmologists. PKP remained the most common surgical technique due to the high incidence of infectious keratitis. However, the use of lamellar keratoplasty, including EK and DALK, significantly increased for other indications. Descemet membrane endothelial keratoplasty was performed mostly in eyes with Fuchs endothelial dystrophy.
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publisher Faculty of Medicine Siriraj Hospital
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spelling doaj-art-6a277ee45f8242e3ae08cb45d56b14ee2025-02-03T07:37:12ZengFaculty of Medicine Siriraj HospitalSiriraj Medical Journal2228-80822025-02-0177210.33192/smj.v77i2.268932Indications and Current Surgical Techniques for Keratoplasty: A 10-year Review from 2011 through 2020 at a Tertiary Referral Hospital in ThailandWipawee Booranapong0Chayanit Junsangsri1Chareenun Chirapapaisan2Panotsom Ngowyutagon3Sathiya Kengpunpanich4Department of Ophthalmology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandDepartment of Ophthalmology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandDepartment of Ophthalmology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandDepartment of Ophthalmology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandDepartment of Ophthalmology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand Objective: To report the indications and current trends in surgical techniques for keratoplasty over 10 years at Siriraj Hospital. Materials and Methods: We retrospectively reviewed the medical records of hospitalized patients who underwent keratoplasty from 2011 to 2020. The collected data comprised demographics, indications for keratoplasty, and surgical techniques used. Results: A total of 754 eyes were included. Active infectious keratitis was the most common indication (26.1%), followed by bullous keratopathy (20.8%) and regraft (19.2%). There was no significant change in indications for keratoplasty between the first 5-year period and the second 5-year period. Fungal keratitis remained the most common etiology for keratoplasty. Penetrating keratoplasty (PKP) was the most common procedure overall (90.7%), followed by endothelial keratoplasty (EK; 5.7%) and deep anterior lamellar keratoplasty (DALK; 3.6%). However, surgical techniques used in the second 5-year period differed significantly from those in the first 5-year period (P < 0.05). The use of PKP decreased from 96.0% to 86.7%; however, EK increased from 1.5% to 8.9%, while DALK rose slightly from 2.5% to 4.4%. Conclusion: Active infectious keratitis was the most common indication for keratoplasty, followed by bullous keratopathy and regraft. These indications may be reduced through collaborative efforts among government leaders, public health officers, and ophthalmologists. PKP remained the most common surgical technique due to the high incidence of infectious keratitis. However, the use of lamellar keratoplasty, including EK and DALK, significantly increased for other indications. Descemet membrane endothelial keratoplasty was performed mostly in eyes with Fuchs endothelial dystrophy. https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/268932 Indications for keratoplasty corneal transplantation penetrating keratoplastydeep anterior lamellar keratoplastyDescemet membrane endothelial keratoplasty
spellingShingle Wipawee Booranapong
Chayanit Junsangsri
Chareenun Chirapapaisan
Panotsom Ngowyutagon
Sathiya Kengpunpanich
Indications and Current Surgical Techniques for Keratoplasty: A 10-year Review from 2011 through 2020 at a Tertiary Referral Hospital in Thailand
Siriraj Medical Journal
Indications for keratoplasty
corneal transplantation
penetrating keratoplasty
deep anterior lamellar keratoplasty
Descemet membrane endothelial keratoplasty
title Indications and Current Surgical Techniques for Keratoplasty: A 10-year Review from 2011 through 2020 at a Tertiary Referral Hospital in Thailand
title_full Indications and Current Surgical Techniques for Keratoplasty: A 10-year Review from 2011 through 2020 at a Tertiary Referral Hospital in Thailand
title_fullStr Indications and Current Surgical Techniques for Keratoplasty: A 10-year Review from 2011 through 2020 at a Tertiary Referral Hospital in Thailand
title_full_unstemmed Indications and Current Surgical Techniques for Keratoplasty: A 10-year Review from 2011 through 2020 at a Tertiary Referral Hospital in Thailand
title_short Indications and Current Surgical Techniques for Keratoplasty: A 10-year Review from 2011 through 2020 at a Tertiary Referral Hospital in Thailand
title_sort indications and current surgical techniques for keratoplasty a 10 year review from 2011 through 2020 at a tertiary referral hospital in thailand
topic Indications for keratoplasty
corneal transplantation
penetrating keratoplasty
deep anterior lamellar keratoplasty
Descemet membrane endothelial keratoplasty
url https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/268932
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AT chayanitjunsangsri indicationsandcurrentsurgicaltechniquesforkeratoplastya10yearreviewfrom2011through2020atatertiaryreferralhospitalinthailand
AT chareenunchirapapaisan indicationsandcurrentsurgicaltechniquesforkeratoplastya10yearreviewfrom2011through2020atatertiaryreferralhospitalinthailand
AT panotsomngowyutagon indicationsandcurrentsurgicaltechniquesforkeratoplastya10yearreviewfrom2011through2020atatertiaryreferralhospitalinthailand
AT sathiyakengpunpanich indicationsandcurrentsurgicaltechniquesforkeratoplastya10yearreviewfrom2011through2020atatertiaryreferralhospitalinthailand