PGC1α −1 Nucleosome Position and Splice Variant Expression and Cardiovascular Disease Risk in Overweight and Obese Individuals

PGC1α, a transcriptional coactivator, interacts with PPARs and others to regulate skeletal muscle metabolism. PGC1α undergoes splicing to produce several mRNA variants, with the NTPGC1α variant having a similar biological function to the full length PGC1α (FLPGC1α). CVD is associated with obesity an...

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Bibliographic Details
Main Authors: Tara M. Henagan, Laura K. Stewart, Laura A. Forney, Lauren M. Sparks, Neil Johannsen, Timothy S. Church
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/2014/895734
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