Ankle-Brachial Index Is a Powerful Predictor of Renal Outcome and Cardiovascular Events in Patients with Chronic Kidney Disease
Ankle-brachial index (ABI) is an accurate tool to diagnose peripheral arterial disease. The aim of this study was to evaluate whether ABI is also a good predictor of renal outcome and cardiovascular events in patients with chronic kidney disease (CKD). We enrolled 436 patients with stage 3–5 CKD who...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2012-01-01
|
| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/2012/238494 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832558802526797824 |
|---|---|
| author | Fu-An Chen Chih-Yu Yang Wu-Chang Yang Jinn-Yang Chen Yee-Yung Ng Szu-Yuan Li Wen-Sheng Liu Shiao-Ti Cheng Yu-Jen Wang Chih-Ching Lin |
| author_facet | Fu-An Chen Chih-Yu Yang Wu-Chang Yang Jinn-Yang Chen Yee-Yung Ng Szu-Yuan Li Wen-Sheng Liu Shiao-Ti Cheng Yu-Jen Wang Chih-Ching Lin |
| author_sort | Fu-An Chen |
| collection | DOAJ |
| description | Ankle-brachial index (ABI) is an accurate tool to diagnose peripheral arterial disease. The aim of this study was to evaluate whether ABI is also a good predictor of renal outcome and cardiovascular events in patients with chronic kidney disease (CKD). We enrolled 436 patients with stage 3–5 CKD who had not been undergoing dialysis. Patients were stratified into two groups according to the ABI value with a cut point of 0.9. The composite renal outcome, including doubling of serum creatinine level and commencement of dialysis, and the incidence of cardiovascular events were compared between the two groups. After a median follow-up period of 13 months, the lower ABI group had a poorer composite renal outcome (OR=2.719, P=0.015) and a higher incidence of cardiovascular events (OR=3.260, P=0.001). Our findings illustrated that ABI is a powerful predictor of cardiovascular events and renal outcome in patients with CKD. |
| format | Article |
| id | doaj-art-6a0b835672804edf81ba7bd7ff4455c9 |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-6a0b835672804edf81ba7bd7ff4455c92025-02-03T01:31:34ZengWileyThe Scientific World Journal1537-744X2012-01-01201210.1100/2012/238494238494Ankle-Brachial Index Is a Powerful Predictor of Renal Outcome and Cardiovascular Events in Patients with Chronic Kidney DiseaseFu-An Chen0Chih-Yu Yang1Wu-Chang Yang2Jinn-Yang Chen3Yee-Yung Ng4Szu-Yuan Li5Wen-Sheng Liu6Shiao-Ti Cheng7Yu-Jen Wang8Chih-Ching Lin9School of Medicine, National Yang-Ming University, No. 155, Section 2, Linong Street, Taipei, TaiwanSchool of Medicine, National Yang-Ming University, No. 155, Section 2, Linong Street, Taipei, TaiwanSchool of Medicine, National Yang-Ming University, No. 155, Section 2, Linong Street, Taipei, TaiwanSchool of Medicine, National Yang-Ming University, No. 155, Section 2, Linong Street, Taipei, TaiwanSchool of Medicine, National Yang-Ming University, No. 155, Section 2, Linong Street, Taipei, TaiwanSchool of Medicine, National Yang-Ming University, No. 155, Section 2, Linong Street, Taipei, TaiwanSchool of Medicine, National Yang-Ming University, No. 155, Section 2, Linong Street, Taipei, TaiwanDepartment of Nursing, Taipei Veterans General Hospital, No. 201, Section 2, Shih-Pai Road, Taipei, TaiwanSchool of Medicine, National Yang-Ming University, No. 155, Section 2, Linong Street, Taipei, TaiwanSchool of Medicine, National Yang-Ming University, No. 155, Section 2, Linong Street, Taipei, TaiwanAnkle-brachial index (ABI) is an accurate tool to diagnose peripheral arterial disease. The aim of this study was to evaluate whether ABI is also a good predictor of renal outcome and cardiovascular events in patients with chronic kidney disease (CKD). We enrolled 436 patients with stage 3–5 CKD who had not been undergoing dialysis. Patients were stratified into two groups according to the ABI value with a cut point of 0.9. The composite renal outcome, including doubling of serum creatinine level and commencement of dialysis, and the incidence of cardiovascular events were compared between the two groups. After a median follow-up period of 13 months, the lower ABI group had a poorer composite renal outcome (OR=2.719, P=0.015) and a higher incidence of cardiovascular events (OR=3.260, P=0.001). Our findings illustrated that ABI is a powerful predictor of cardiovascular events and renal outcome in patients with CKD.http://dx.doi.org/10.1100/2012/238494 |
| spellingShingle | Fu-An Chen Chih-Yu Yang Wu-Chang Yang Jinn-Yang Chen Yee-Yung Ng Szu-Yuan Li Wen-Sheng Liu Shiao-Ti Cheng Yu-Jen Wang Chih-Ching Lin Ankle-Brachial Index Is a Powerful Predictor of Renal Outcome and Cardiovascular Events in Patients with Chronic Kidney Disease The Scientific World Journal |
| title | Ankle-Brachial Index Is a Powerful Predictor of Renal Outcome and Cardiovascular Events in Patients with Chronic Kidney Disease |
| title_full | Ankle-Brachial Index Is a Powerful Predictor of Renal Outcome and Cardiovascular Events in Patients with Chronic Kidney Disease |
| title_fullStr | Ankle-Brachial Index Is a Powerful Predictor of Renal Outcome and Cardiovascular Events in Patients with Chronic Kidney Disease |
| title_full_unstemmed | Ankle-Brachial Index Is a Powerful Predictor of Renal Outcome and Cardiovascular Events in Patients with Chronic Kidney Disease |
| title_short | Ankle-Brachial Index Is a Powerful Predictor of Renal Outcome and Cardiovascular Events in Patients with Chronic Kidney Disease |
| title_sort | ankle brachial index is a powerful predictor of renal outcome and cardiovascular events in patients with chronic kidney disease |
| url | http://dx.doi.org/10.1100/2012/238494 |
| work_keys_str_mv | AT fuanchen anklebrachialindexisapowerfulpredictorofrenaloutcomeandcardiovasculareventsinpatientswithchronickidneydisease AT chihyuyang anklebrachialindexisapowerfulpredictorofrenaloutcomeandcardiovasculareventsinpatientswithchronickidneydisease AT wuchangyang anklebrachialindexisapowerfulpredictorofrenaloutcomeandcardiovasculareventsinpatientswithchronickidneydisease AT jinnyangchen anklebrachialindexisapowerfulpredictorofrenaloutcomeandcardiovasculareventsinpatientswithchronickidneydisease AT yeeyungng anklebrachialindexisapowerfulpredictorofrenaloutcomeandcardiovasculareventsinpatientswithchronickidneydisease AT szuyuanli anklebrachialindexisapowerfulpredictorofrenaloutcomeandcardiovasculareventsinpatientswithchronickidneydisease AT wenshengliu anklebrachialindexisapowerfulpredictorofrenaloutcomeandcardiovasculareventsinpatientswithchronickidneydisease AT shiaoticheng anklebrachialindexisapowerfulpredictorofrenaloutcomeandcardiovasculareventsinpatientswithchronickidneydisease AT yujenwang anklebrachialindexisapowerfulpredictorofrenaloutcomeandcardiovasculareventsinpatientswithchronickidneydisease AT chihchinglin anklebrachialindexisapowerfulpredictorofrenaloutcomeandcardiovasculareventsinpatientswithchronickidneydisease |