ZSH‐2208: A novel retinoid with potent anti‐tumour effects on ESCC stem cells via RARγ–TNFAIP3 axis

ZSH‐2208: A novel retinoid with potent anti‐tumour effects on ESCC stem cells via RARγ–TNFAIP3 axis

Abstract Backgroud Oesophageal cancer ranks among the most prevalent malignant tumours globally, primarily consisting of oesophageal squamous cell carcinoma (ESCC). Cancer stem cells (CSCs) accelerate the progression ESCC via their strong self‐renewal and tumourigenic capabilities, presenting signif...

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Bibliographic Details
Main Authors: Ruoxue Chen, Xuan Huang, Jiayun Hou, Junjie Ni, Wenrui Zhao, Quanlin Li, Heng Jiao, Xin Cao
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Clinical and Translational Medicine
Subjects:
oesophageal squamous cell carcinoma
retinoid
retinoid acid receptor γ
TNFAIP3
tumour‐repopulating cells
ZSH‐2208
Online Access:https://doi.org/10.1002/ctm2.70148
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