Exacerbation of Ulcerative Colitis following Administration of 5-ASA Enemas
A 33-year-old female with a 15 year history of ulcerative colitis presented with worsening diarrhea following colectomy and ileorectal anastomosis six months previously. Following administration of 5-ASA enemas (Salofalk). the patient developed abdominal cramps. nausea and vomiting. and severe diarr...
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Format: | Article |
Language: | English |
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Wiley
1989-01-01
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Series: | Canadian Journal of Gastroenterology |
Online Access: | http://dx.doi.org/10.1155/1989/461926 |
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author | Barbara A. Young Robin S. McLeod Zane Cohen |
author_facet | Barbara A. Young Robin S. McLeod Zane Cohen |
author_sort | Barbara A. Young |
collection | DOAJ |
description | A 33-year-old female with a 15 year history of ulcerative colitis
presented with worsening diarrhea following colectomy and ileorectal anastomosis
six months previously. Following administration of 5-ASA enemas (Salofalk).
the patient developed abdominal cramps. nausea and vomiting. and severe diarrhea
resulting in hypotension. Symptoms abated quickly when the 5-ASA enemas,
were discontinued. Although diarrhea and abdominal cramps have been
described previously as side effects of oral sulfasalazine. oral 5-ASA and sulfasalazine
enemas, this is the first report of these symptoms occurring following administration
of 5-ASA enemas. |
format | Article |
id | doaj-art-69cfff5f1eaf495b8b6be2fc4a6611df |
institution | Kabale University |
issn | 0835-7900 |
language | English |
publishDate | 1989-01-01 |
publisher | Wiley |
record_format | Article |
series | Canadian Journal of Gastroenterology |
spelling | doaj-art-69cfff5f1eaf495b8b6be2fc4a6611df2025-02-03T01:29:11ZengWileyCanadian Journal of Gastroenterology0835-79001989-01-0132505210.1155/1989/461926Exacerbation of Ulcerative Colitis following Administration of 5-ASA EnemasBarbara A. Young0Robin S. McLeod1Zane Cohen2Division of General Surgery and Departments of Surgery and Pharmacy, Toronto General Hospital, University of Toronto, Toronto, Ontario, CanadaDivision of General Surgery and Departments of Surgery and Pharmacy, Toronto General Hospital, University of Toronto, Toronto, Ontario, CanadaDivision of General Surgery and Departments of Surgery and Pharmacy, Toronto General Hospital, University of Toronto, Toronto, Ontario, CanadaA 33-year-old female with a 15 year history of ulcerative colitis presented with worsening diarrhea following colectomy and ileorectal anastomosis six months previously. Following administration of 5-ASA enemas (Salofalk). the patient developed abdominal cramps. nausea and vomiting. and severe diarrhea resulting in hypotension. Symptoms abated quickly when the 5-ASA enemas, were discontinued. Although diarrhea and abdominal cramps have been described previously as side effects of oral sulfasalazine. oral 5-ASA and sulfasalazine enemas, this is the first report of these symptoms occurring following administration of 5-ASA enemas.http://dx.doi.org/10.1155/1989/461926 |
spellingShingle | Barbara A. Young Robin S. McLeod Zane Cohen Exacerbation of Ulcerative Colitis following Administration of 5-ASA Enemas Canadian Journal of Gastroenterology |
title | Exacerbation of Ulcerative Colitis following Administration of 5-ASA Enemas |
title_full | Exacerbation of Ulcerative Colitis following Administration of 5-ASA Enemas |
title_fullStr | Exacerbation of Ulcerative Colitis following Administration of 5-ASA Enemas |
title_full_unstemmed | Exacerbation of Ulcerative Colitis following Administration of 5-ASA Enemas |
title_short | Exacerbation of Ulcerative Colitis following Administration of 5-ASA Enemas |
title_sort | exacerbation of ulcerative colitis following administration of 5 asa enemas |
url | http://dx.doi.org/10.1155/1989/461926 |
work_keys_str_mv | AT barbaraayoung exacerbationofulcerativecolitisfollowingadministrationof5asaenemas AT robinsmcleod exacerbationofulcerativecolitisfollowingadministrationof5asaenemas AT zanecohen exacerbationofulcerativecolitisfollowingadministrationof5asaenemas |