Development of a Cell-Based Functional Assay for the Detection of Clostridium botulinum Neurotoxin Types A and E
The standard procedure for definitive detection of BoNT-producing Clostridia is a culture method combined with neurotoxin detection using a standard mouse bioassay (MBA). The mouse bioassay is highly sensitive and specific, but it is expensive and time-consuming, and there are ethical concerns due t...
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Main Authors: | Uma Basavanna, Tim Muruvanda, Eric W. Brown, Shashi K. Sharma |
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Format: | Article |
Language: | English |
Published: |
Wiley
2013-01-01
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Series: | International Journal of Microbiology |
Online Access: | http://dx.doi.org/10.1155/2013/593219 |
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