Plants Metabolites as In Vitro Inhibitors of SARS-CoV-2 Targets: A Systematic Review and Computational Analysis

Plants Metabolites as In Vitro Inhibitors of SARS-CoV-2 Targets: A Systematic Review and Computational Analysis

Background/Objectives: Since the emergence of the COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the discovery of compounds with antiviral potential from medicinal plants has been extensively researched. This study aimed to investigate plant metabolites wit...

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Main Authors: Brendo Araujo Gomes, Diégina Araújo Fernandes, Thamirys Silva da Fonseca, Mariana Freire Campos, Patrícia Alves Jural, Marcos Vinicius Toledo e Silva, Larissa Esteves Carvalho Constant, Andrex Augusto Silva da Veiga, Beatriz Ribeiro Ferreira, Ellen Santos Magalhães, Hagatha Bento Mendonça Pereira, Beatriz Graziela Martins de Mattos, Beatriz Albuquerque Custódio de Oliveira, Stephany da Silva Costa, Flavia Maria Mendonça do Amaral, Danilo Ribeiro de Oliveira, Ivana Correa Ramos Leal, Gabriel Rocha Martins, Gilda Guimarães Leitão, Diego Allonso, Simony Carvalho Mendonça, Marcus Tullius Scotti, Suzana Guimarães Leitão
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Drugs and Drug Candidates
Subjects:
natural products
3CL<sub>pro</sub>
PL<sub>pro</sub>
Spike:ACE2
RdRp
ADMET profiling
Online Access:https://www.mdpi.com/2813-2998/4/2/27
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